Epithelia Flashcards
Explain the position of the basement membrane
Between epithelia cells and connective tissue
Define epithelia
Sheets of contiguous cells, of varied embryonic origin that cover the external surfaces of the body and line internal surfaces
Explain structure of the basement membrane
Basal lamina laid down by epithelial cells closest, thickness varied by changing layer of reticular fibres
Explain the function of the basement membrane
Strong flexible layer for epithelial cells to adhere to
Cellular and molecular filter
Describe simple epithelia
One cell layer thick
Describe stratified/compound epithelia
More than one cell layer thick
Describe pseudostratified epithelia
Single layer but appears layered
E.g. URT - secretion and conduit
Epididymis - absorption
Describe squamous epithelia
Flat, scale like can be keratinised for extra protection Pericardium,peritoneum - lubrication Alveoli - gas exchange Bowmans capsule - barrier Endothelium - at via pinocytes
Describe cuboidal epithelia
Cube shaped Exocrine glands - absorption and conduit Kidney tubules - absorption and secretion Ovary - barrier Thyroid - hormone synthesis and storage
Describe columnar epithelium
Rectangle Small intestine and colon - absorption Stomach lining, colon - secretion Small intestine , colon - lubrication Oviduct - transport
Describe transitional epithelium
Can stretch and distend e.g.bladder ureter urethra
Why does epidermal epithelia have a longer renewal rate than epithelia of the small intestine?
Depends on function, 28 days in dermis as migration, keratinisation, death and sloughing take a while, only 4-6 in small intestine as constantly processing food
What is metaplasia?
Change of one type of epithelium to another, in heavy smokers pseudostratified Collumnar goes to stratified squamous for more protection
What is neoplasia
Change in epithelia results in tumour growth
Why are only basal layer of cells in contact with the basement membrane?
Basement membrane separates epithelium from underlying connective tissue, layers of epithelium rest upon it