connective tissue

Question 0

what are fibroblasts

Answer 0

secrete ground substance and fibres

Question 1

define connective tissue

Answer 1

a tissue that connects, supports, binds or separates other tissues and organs, mesodermally derived, made up of cells, extracellular fibres and ground substance

Question 2

what are macrophages

Answer 2

phagocytosis and antigen presenting cells

Question 3

what are mast cells

Answer 3

granules which contain histamine

Question 4

what are mesenchymal cells in connective tissue?

Answer 4

undifferentiated - to maintain extracellular matrix

Question 5

what is ground substance?

Answer 5

hyaluronate proteoglycan aggregates with gag units that attract water

Question 6

what are the function of collagen fibres within connective tissue

Answer 6

interweave proteoglycan monomers

Question 7

what is the function of elastic fibres in connectie tissue

Answer 7

allow stretch due to lysine

Question 8

describe loose connective tissue

Answer 8

forms a framework around structures
high ratio of ground substance in which all structures lie
e.g. areolar, reticular, adipose

Question 9

describe regular dense connective tissue

Answer 9

closely packed fibres that run uni-directionally to give good tensile strength e.g. tendons

Question 10

describe irregular connective tissue

Answer 10

closely packed fibres tht run multi-directionally for multidirectional force resistance e.g.dermis

Question 11

what is marphans syndrome?

Answer 11

utation in fibrillin gene - disorder of elastin - tissue irregularity

Question 12

what is ehlers-danlos?

Answer 12

consequence of collagen abnormalaties of dermis and tendons - joint dislocations and skin deformation

Question 13

what is systematic sclerosis

Answer 13

excessive collagen in organs, causes hardening and functional impairment

Question 14

what is the function of elastic fibres?

Answer 14

alveolar walls maintain shape ad protection during distersion

Question 15

what is the function of reticular fibres?

Answer 15

form a structural framework around organs e.g. liver

Question 16

what is the function of mucous connective tissue?

Answer 16

in umbilical
component cells - large stellate fibroblasts which fuse with adjacent cells
loose amorphous connective tissue with jelly like matrix formed from hykaronic acid sparsly populated type 1 and 3 collagen fibres and fibroblasts

Question 17

describe aerolar connective tissue

Answer 17

formed by differentiation of cells from the mesochyme
loosly aranged fibroelastic connective tissue
stretch as just uner skin
forms submucosa beneath epithelia of mm
contains fibroblasts, macrophages and mast cels
collagen fibres and elastin for branching network

Question 18

describe adipose tissue

Answer 18

cells between llagen fibres
unstained as fat dissolves during processing
insulation and shock absorber
can generate heat

Question 19

describe the dermis

Answer 19

immediately below the epidermis
thick layer of onnective tissue containing blood vessels,lymphatics, skin eppendages sensory nerves and nerve endings
inly thick collagen fibres
variable amount of elastic fibres

Question 20

describe tendons

Answer 20

connect muscle to bone
parallel bunches of collaen
interspersed with rows of flattened fibroblasts
groups of collagen fibres and fibroblasts form fasicles
fasicles seperated by loose connective tissuegroups of fasicles held together by peritndioum
fibrous sheath surrounds the whole tendon