Epilepsy PART2 (Antiepileptic Drugs) Flashcards
Which of the following mechanisms is included in the action of antiepileptic drugs?
a. Enhancing excitatory glutamate transmission.
b. Blocking voltage-gated channels (Na⁺ or Ca²⁺).
c. Reducing inhibitory γ-aminobutyric acid (GABA)-ergic impulses.
d. Increasing excitatory serotonin transmission.
The correct answer is: b. Blocking voltage-gated channels (Na⁺ or Ca²⁺).
Which of the following is true regarding the mechanisms of action of antiepileptic drugs?
a. They only block voltage-gated Na⁺ channels.
b. They enhance inhibitory γ-aminobutyric acid (GABA)-ergic impulses.
c. They interfere with inhibitory glutamate transmission.
d. They do not affect voltage-gated channels.
The correct answer is: b. They enhance inhibitory γ-aminobutyric acid (GABA)-ergic impulses.
Which mechanism is NOT a part of antiepileptic drug action?
a. Interfering with excitatory glutamate transmission.
b. Enhancing inhibitory GABAergic impulses.
c. Blocking voltage-gated channels.
d. Enhancing excitatory serotonin transmission.
The correct answer is: d. Enhancing excitatory serotonin transmission.
True or False: Antiepileptic drugs work by enhancing excitatory glutamate transmission.
a. True.
b. False.
The correct answer is: b. False.
Which of the following correctly describes a mechanism of action of antiepileptic drugs?
a. Interfering with excitatory serotonin transmission.
b. Blocking voltage-gated potassium channels.
c. Enhancing inhibitory GABAergic impulses.
d. Reducing excitatory dopamine transmission.
The correct answer is: c. Enhancing inhibitory GABAergic impulses.
Which of the following drugs is classified as a 1st generation antiepileptic?
a. Gabapentin
b. Lamotrigine
c. Phenobarbital
d. Topiramate
The correct answer is: c. Phenobarbital.
Which of the following is a 2nd generation antiepileptic drug?
a. Phenytoin
b. Carbamazepine
c. Ethosuximide
d. Gabapentin
The correct answer is: d. Gabapentin.
True or False: Valproic acid is a 1st generation antiepileptic drug.
a. True.
b. False.
The correct answer is: a. True.
Which of the following drugs is NOT a 1st generation antiepileptic?
a. Divalproex
b. Levetiracetam
c. Ethosuximide
d. Carbamazepine
The correct answer is: b. Levetiracetam.
Which of the following drugs is classified as a 2nd generation antiepileptic?
a. Phenobarbital
b. Phenytoin
c. Lamotrigine
d. Divalproex
The correct answer is: c. Lamotrigine.
True or False: Oxcarbazepine is a 2nd generation antiepileptic drug.
a. True.
b. False.
The correct answer is: a. True.
Which of the following drugs belongs to the 1st generation antiepileptic category?
a. Gabapentin
b. Zonisamide
c. Phenytoin
d. Levetiracetam
The correct answer is: c. Phenytoin.
Which of the following is a 2nd generation antiepileptic drug?
a. Valproic acid
b. Carbamazepine
c. Topiramate
d. Ethosuximide
The correct answer is: c. Topiramate.
True or False: Phenobarbital is a 2nd generation antiepileptic drug.
a. True.
b. False.
The correct answer is: b. False.
Which of the following is NOT a 2nd generation antiepileptic drug?
a. Gabapentin
b. Lamotrigine
c. Phenobarbital
d. Levetiracetam
The correct answer is: c. Phenobarbital.
Which of the following drugs is classified as a 1st generation antiepileptic?
a. Levetiracetam
b. Divalproex
c. Topiramate
d. Zonisamide
The correct answer is: b. Divalproex.
True or False: Zonisamide is a 1st generation antiepileptic drug.
a. True.
b. False.
The correct answer is: b. False.
Which of the following is a 1st generation antiepileptic drug?
a. Gabapentin
b. Lamotrigine
c. Ethosuximide
d. Oxcarbazepine
The correct answer is: c. Ethosuximide.
Which of the following drugs belongs to the 2nd generation antiepileptic category?
a. Phenytoin
b. Carbamazepine
c. Topiramate
d. Valproic acid
The correct answer is: c. Topiramate.
True or False: Lamotrigine is a 2nd generation antiepileptic drug.
a. True.
b. False.
The correct answer is: a. True.
Benzodiazepines bind to which receptors to reduce the firing rate?
a. Dopamine receptors
b. Serotonin receptors
c. GABA inhibitory receptors
d. Glutamate receptors
The correct answer is: c. GABA inhibitory receptors.
True or False: Benzodiazepines reduce the firing rate by binding to GABA inhibitory receptors.
a. True.
b. False.
The correct answer is: a. True.
Which of the following benzodiazepines is used for myoclonic seizures?
a. Clonazepam
b. Lorazepam
c. Diazepam
d. Both b and c
The correct answer is: d. Both b and c.
True or False: Diazepam is used for partial and generalized tonic-clonic seizures.
a. True.
b. False.
The correct answer is: a. True.