Epilepsy Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

1st line mx of generalised tonic-clonic seizures?

A

Carbamazepine
Lamotrigdine
Sodium valproate
Oxcarbazepine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the mx of tonic or absence seizures?

A

Sodium valproate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What epilepsy meds are enzyme inducers?

A

Carbamazepine (reduces efficacy other AEDs)

Phenytoin (reduces efficacy other AEDs)

Sodium valproate (increases level of other AEDs)

Topiramate (weak inducer)

Oxcarbazepine (weak inducer)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What epilepsy meds are susceptible to enzyme inducers?

A

Lamotrigine
Tiagabine
Levetiracetam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is first line mx of absence seizures?

A

Ethosuximide
Lamotrigine
Sodium valproate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is second line for tonic-clonic seizures?

A
Clobazepam
Lamotrigine 
Sodium valproate
Levetiracetam 
Topiramate
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the SEs of carbamazepine?

A

Strong enzyme inducer- affects other AED and OCP.

Reduced bone density

Auto induction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the SEs of phenytoin?

A

Strong enzyme inducer- affects other AED and OCP.

Susceptible to other inducers

Reduced bone density

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What drug interactions does gabapentin have?

A

None significant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What drug interactions does levetiracetam have?

A

None significant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What drug interactions does pregabalin have?

A

None significant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the rules for driving a car or motorcycle when epileptic?

A

1 year since last seizure before license allowed.

Not allowed during and for 6 months after medication has been changed

Once compliant with treatment driving allowed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the rules for driving an HGV, bus or large vehicle when epileptic?

A

No seizures for 10 years before licence granted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What anticonvulsants are safe in pregnancy?

A

Lamotrigine apparently safe

Folate supplementation essential

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What AED should be absolutely avoided in pregnancy?

A

Sodium valproate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which is the safest old AED during pregnancy?

A

Carbamazepine