Antibiotics Flashcards
What do you prescribe for CAP?
Cefuroxime/amoxicillin + clarithromycin/erythromycin
What do you prescribe for HAP?
Need to cover gram negative:
Cefotaxime + piperacillin or similar + quinolone
Early after admission: Co-amoxiclav/ceftaxidime/ciprofloxacin
What do you prescribe for COPD exacerbations?
Amoxicillin/co-amoxiclav/doxycylcin/erythromycin
What do you prescribe for endocarditis?
Benpen/flucloxacillin/vancomycin + gent/rifampicin
What do you prescribe for meningitis?
cefotaxime/benpen (chloramphenicol)
What do you prescribe for pyelonephritis?
Cephalosporin or quinolone
What do you prescribe for lower UTI?
AMoxicillin/ cefalexin/ quinolone/ trimethoprim/ nitrofurantoin
Avoid quinolones and trimethoprim in pregnancy
What do you prescribe for septicaemia?
Broad spectrum beta-lactam e.g. meropenem, tazocin
Community- broad spectrum cefalosporin
May add amino glycoside ± fluclox or add metronidazole
What do you prescribe for staph infections?
Fluclox or vanc/ fusidate/ aminoglycosides
How many patients with a penicillin allergy will also be allergic to cephalosporins?
5-15%
Which abs do you have to carry out therapeutic drug monitoring for?
Amino glycosides
Vancomycin
Which tetracylines are safe in renal impairment?
Doxycycline
Others not
What abs should be avoided in pregnancy?
Trimethoprim
Quinolone
Doxycycline
Amino glycosides
Do you need to give abx prophylaxis for dental procedures in patients with valve diseases?
No
What abx do you give for c diff?
Metronidazole 2 weeks