epigenetic and phenotype variation Flashcards
1
Q
what is epigenetic profile impacted by
A
environmental condition
2
Q
extrinsic environmental
A
diet, exercise and drugs
3
Q
inherited epigenetic
A
epigenetic programming, repair machinery and environmental factors
4
Q
histone modification
A
internal +external factors increase acetylation of histone tails such as smoking and diet
5
Q
which factors cause inhibition of histone tail acetylation
A
nickel and copper which cause a decrease
6
Q
hypermethylation
A
high level of exposure inactivates genes
7
Q
bi allelic expression
A
both allele transcribed
8
Q
monoalleilic
A
only one allele is expressed
9
Q
genome imprinting
A
epigenetic phenomenon(mechanism) certain genes are expressed mon alleilaclly in parent of origin specific manner
10
Q
uniparental disomy
A
2 chromosomes from one parent happens due to translocation
