Cytoskeleton and cell mechanics Flashcards

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1
Q

microtubule

A

protofilaments go round in a ring where each of them is made up of repetitive alpha and beta(binds GTP) tubular dimers

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2
Q

crystal structure

A

fuel go to the top which is where alpha is and beta is plus end which gives polarity

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3
Q

kinesin

A

moves towards plus end and dumps its content outside membrane by moving to plasma membrane

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4
Q

dynein

A

moves to minus end

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5
Q

b tubulin

A

binds ADP which swings head forward

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6
Q

Dynein organelle transport

A

2 knees move rapidly retains attachment to microtubule as it delivers organelle in opposite direction to the nucleus of the cell

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7
Q

hydrolisation

A

ATP binding force generating stroke pushes dynein then releasing from microtubule to bind the head back down to ADP then goes to minus head

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8
Q

neurofilament

A

consists of obligate heterodimer which helps with support of axon and gilal cells

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