Epidemiology/Ethics Flashcards
in _______ studies, the researcher determines whether the participates are exposed or unexposed and follows them over time for disease development
cohort studies
in _________ studies, the research determines whether the participants have the disease or not and determines if they were exposed or unexposed.
case-control studies
in _______ studies, the researcher determines disease prevalence at one point in time
cross-sectional studies
bias introduced into a study when a clinician is aware of the pt’s tx type
observational bias
bias introduced when a third variable is either positively or negatively associated w/ both the exposure and the outcome variables, inducing an incorrect association
confounding bias
bias introduced as a result from differences in retrospective recall of past factors or outcomes
recall bias
bias introduced as a result from earlier detection of disease, giving an appearance of prolonged survival when in fact that natural course is not altered
lead-time bias
type of error - defined as the probability of concluding that there is a difference in tx effects between groups when in fact there is not (rejecting the null hypothesis when it should not be rejected)
type I (alpha) error
type of error - defined as the probability that there is no difference in tx effects when in fact there is a difference (not rejecting the null hypothesis when it should be rejected)
type II (beta) error
difference between incidence and prevalence?
incidence is the percentage of new cases of disease that develop over a given time period among the total population at risk vs prevalence is the percentage of cases of disease in a population at one snapshot in time
(incidence looks at new cases vs prevalence looks at all current cases)
3 levels of prevention:
- primary prevention - preventive measures that decrease the incidnece of disease
- secondary prevention - preventive measures that focus on identifying the disease early and implementing measures that can halt or slow progression
- tertiary prevention - preventive measures that decrease the morbidity or mortality resulting from the presence of disease
health screening for women 19-39 y/o
pap q 2yrs at 21, then q 3yrs at 30; pelvic yearly > 21; g/c yearly from sexual active - 24; HIV at least once
health screening for women 40-49 y/o
mxr q 1-2yrs, pap q 3yrs; pelvic yearly; blood glucose or A1c at 45, then q 3yrs
health screening for women 50-64 y/o
mxr q 1-2yrs, pap q 3yrs; pelvic yearly; blood glucose or A1c q 3yrs; colorectal (fecal occult blood yearly, flex sig q 5yrs, or colonscopy q 10 yrs)
health screening for women >65 y/o
mxr q 1-2yrs; pelvic yearly; blood glucose or A1c q 3yrs; colorectal (fecal occult blood yearly, flex sig q 5yrs, or colonscopy q 10 yrs); DEXA scan