Enzymes And Muscles Flashcards

1
Q

Large animal enzyme chemistry

A

GGT
AST
CK
SDH

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2
Q

Small animal chemistry

A

ALT
ALP

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3
Q

Leakage enzymes

A

AST, CK, ALT, SDH, LDH, AMS, LPS

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4
Q

Induction enzymes

A

GGT ALP

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5
Q

Causes for enzyme increase

A

Hemolysis & lipemia
- renal disease : AMS & LPS
Hyperplasia
- L-GGT & B-ALP
Ingestion - colostrum GGT

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6
Q

Features of creatine kinase

A

Short half life, correlates w severity of damage

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7
Q

Causes for elevated CK

A

Rhabdomyolysis
- capture myopathy
- Exertional myopathy
Recumbence - LA
Hemolysis
Young age
Seizures/strenuous activity
Selenium deficiency

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8
Q

Causes for AST increase

A

Muscle, hepatic, cardiac injury
Longer half life
Resolution - v CK ^ AST
Ongoing disease - ^ CK ^ AST

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9
Q

Features of ALT

A

Long half life
Liver specific is SA
Hemolysis + muscle injury can elevate
Anticonvulsants + steroids great increase
Hyperthyroidism in cats ^^^

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10
Q

Myoglobin vs hemoglobin

A

Hemo - red plasma = hemoglobinuria
Myo - normal plasma = myoglobinemia

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11
Q

Other chemistry markers for muscle injury

A

Hyperkalemia
Hypoatremia
Hypochorlidemia
Hyperphosphatemia
Hypocalcemia

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