(Enochs + some)Lecture 7: Chronic Pain Flashcards
Define pain.
An unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage.
What is the MC reason that people seek medical care?
Pain
What do most opioid OD deaths come from?
Heroin and fentanyl
What is nonmaleficence?
Not doing harm.
Slightly different from doing good. (Beneficence)
How long does acute pain usually last?
Momentarily to 6 months.
At what point is pain considered chronic?
3 months on average.
ASIPP defines it as 6 months.
What is the purpose of chronic pain?
No purpose :(
What kind of chronic pain is adaptable?
Constant chronic pain.
What happens to gray matter in patients with chronic pain?
Decreases.
When is chronic pain mostly treatable?
Within 2 years
What are the 3 NTs that excite pain?
- Substance P
- CGRP (calcitonin gene related peptide)
- Glutamate
What is a nocireceptor?
A receptor that can differentiate between what is painful and not.
Describe an A-beta fiber.
- Thick, myelinated, low threshold mechanoreceptors.
- Associated with light touch, pressure, and hair movement.
Describe an A-delta fiber.
- Thin, myelinated, high and low mechanical + thermal.
- First, Sharp intense pain
Describe a C fiber.
- Unmyelinated, free nerve endings.
- High threshold to all stimuli.
- Majority of afferent fibers
- Prolonged, burning sensation after the A-stimulus
Where are the veins and arteries contained with the spinal cord?
Epidural space
Describe the pathway of pain beginning with peripheral sensory receptors.
- PEripheral sensory receptor
- Dorsal root ganglia
- Dorsal root
- Synapse in dorsal horn/column
- Connect with secondary order neurons
- Goes other contralateral and ascend (lateral spinothalamic)
- Other: ascend ipsilateral, descends, then goes to reflex arc.
What is the anterolateral system?
Describe white matter in the spinal cord.
- Myelinated
- Longitudinal
- Up down
- Signal conduction
High speed internet
Describe gray matter.
- Segmented
- Side to side
- Signal processing
- Also makes up nerve roots
Processors