Endocrinology 2 Flashcards

1
Q

What cardiac defect is acromegaly associated with?

A

Cardiomyopathy

(also HTN)

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2
Q

What are 4 key complications of acromegaly?

A

1) HTN

2) diabetes

3) cardiomyopathy

4) colorectal cancer

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3
Q

Rules surrounding schizophrenia & driving?

A

Patients with schizophrenia must not drive and must notify the DVLA, until stable and well for 3 months and following a suitable psychiatristy report.

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4
Q

What metabolic disturbance is seen in Cushing’s syndrome?

A

Hypokalaemic metabolic alkalosis

(due to increased cortisol levels)

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5
Q

Interpretation of 9am serum cortisol levels in Addison’s:

a) >500 nmol/l

b) <100

c) 100-500

A

a) Addison’s very unlikely

b) definitely abnormal

c) should prompt ACTH stimulation test to be performed

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6
Q

What investigation is used to confirm diagnosis of acromegaly?

A

OGTT with serial GH measurements

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7
Q

Dosing regime in Addison’s?

A

Majority of dose in morning, remainder in evening

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8
Q

Mx of medications in Addison’s patient with intercurrent illness?

A

Double glucocorticoids (hydrocortisone), keep fludrocorticoids (fludrocortisone) the same

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9
Q
A
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