Endocrinology

Question 1

What are the various possible effects Amiodarone can have on thyroid function?

Answer 1

Amiodarone causes thyroid disturbance in 1 in 6 patients on it - can cause both hypo and hyper by increasing iodine levels

Amiodarone-induced hypothyroidism

Amiodarone-induced hyperthyroidism type I (direct result of excess iodine)-> goitre present -> treatment is Carbimazole or Potassium Perchlorate

Amiodarone-induced hyperthyroidism type 2 (a destructive thyroiditis) - NO goitre -> Tx is with steroids