ENDOCRINE SYSTEM Session 8 Flashcards
What do the endocrine and exocrine glands both do ?
- Exocrine glands : Secrete their products into ducts
- Endocrine glands : secrete their products into the bloodstream , which delivers them throughout the body
What type of cell is the only one that can respond to a hormone ?
- Target cells , they have receptor proteins for that hormone
What are some example of peptide hormones ?
- Peptides , proteins , glycoprotein and modified amino acids
What are steroid hormones derived from and what structure do they have ?
- Derived from cholesterol , and all have sample complex of four carbon rings
What is an enzyme cascade and what is the first step in it ?
- The first step is that cyclin adenosine monophosphate ( cAMP ) is formed.
- Enzyme cascade is when activation of one enzyme leads to another enzyme being activated and its carried on.
How do peptide hormones interact with target cells ?
- Peptide Hormones usually does not enter target cells , there fore there is another hormone called the first messenger which activates another hormone called second messenger to carry on .
Which 3 places are the only locations in the body that produces steroid hormones ?
- Adrenal Cortex
- Ovaries
- Testes
What do the steroid hormones bind to ?
- They do not bind to plasma membrane receptors and since they are hydrophobic , they are able to cross the plasma membrane and it binds to a receptor in the nucleus or cytoplasm
What does the steroid hormone do inside the nucleus once binded to a receptor ?
- It then binds with DNA and activates certain genes and mRNA moves to the ribosomes and protein synthesis follows
What does the hypothalamus do ?
- it links the nervous and endocrine systems together
- Regulates the internal environment via the autonomic nervous system
What helps to connect the pituitary gland to the hypothalamus
- A stalk ( infundibulum )
What do the neurosecretory cells in the hypothalamus produce and where are they stored after ?
- Antidiuretic Hormone (ADH)
- Oxytocin
- they are then stored in the posterior pituitary
What happens when blood is too concentrated ?
- ADH is released form the posterior pituitary and it causes more water to be reabsorbed Into kidney capillaries and then when blood becomes dilute , ADH is no longer released
What is diabetes insidious and what does cause ?
- It is the inability to produce ADH
- It also produces large amounts of urine , resulting in severe dehydration and loss of important ions
What does oxytocin do ?
- Causes uterine contractions during childbirth and milk letdown during breastfeeding