endocrine system 2 Flashcards

1
Q

thyroid gland

A

thyroxine
triiodothyronine
calcitonin

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2
Q

adrenal glands

A

adrenal medulla = epinephrine & norepinephrine
adrenal cortex = cortisol, corticosterone, aldosterone & androgens

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3
Q

pancreatic islets

A

insulin
glucagon

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4
Q

pituitary hormones

A

ACTH
TSH
GH
PRL
PSH
LH
OXT
ADH

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5
Q

effects of GH

A

acts on liver
promotes release of somatomedins eg insulin
stimulate tissue repair
increase aa uptake

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6
Q

posterior pituitary hormones

A

ADH
Oxytocin

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7
Q

oxytocin

A

targets in male smooth muscle in ductus deferens and prostate gland
females uterine smooth muscle and mammary glands

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8
Q

ADH

A

acts on kidneys for water reabsorption, elevation of blood pressure and volume

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9
Q

pineal gland neurons

A

collaterals from vision pathways

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10
Q

what do pinealocytes do

A

secrete melatonin for circadian rhythm and antioxidant

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11
Q

thyroid gland location

A

anterior to thyroid cartilage of larynx

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12
Q

thyroid gland structure

A

2 lobes connected by narrow isthmus

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13
Q

role of thyroid hormones

A

increase sodium potassium ATPase production

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14
Q

effects of thyroid hormones

A

increase o2 consumption
increase hr
increase sensitivity to sympathetic stimulation
stimulate rbc formation
increase bone turnover

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15
Q

thyroid follicles

A

hollow spheres lined by cuboidal epithelium
contain colloid (protein fluid)

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16
Q

Rolle of thyroid follicles

A

synthesis tryosine rich thyroglobulin and incorporate iodine

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17
Q

cause of thyroid gland swelling

A

lack of iodine

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18
Q

c cells

A

produce calcitonin
reduces serum calcium
deposition in bone and excretion by kidney

19
Q

role of calcitonin in regulation of calcium ion conc

A

thyroid glands produces =
increase excretion and deposition in bone =
homeostasis restored and blood levels decline =
normal calcium in blood =
rising levels =
back to start

20
Q

role of PTH in regulation of calcium ion conc

A

normal blood level =
falling calcium levels =
parathyroid secrete PTH =
increase reabsorption by kidneys, ca release from bone & increase calcitriol =
increase ca levels

21
Q

parathyroid glands

A

posterior thyroid
cells produce PTH

22
Q

role of PTH

A

increase serum calcium

23
Q

adrenal cortex releases …

A

steroid hormones

24
Q

adrenal medulla releases …

A

catecholamines eg fight or flight

25
sections of adrenal cortex
zona reticularis - androgens zona fasciculata - glucorticoids zona glomerulosa - mineralocorticoids
26
androgens
anabolic effects
27
glucorticoids
cortisol promoting glucose synthesis, fat and protein catabolism and anti inflammatory
28
glucorticoids
cortisol promoting glucose synthesis, fat and protein catabolism and anti inflammatory
29
mineralocorticoids
effect electrolyte consumption
30
pancreatic islets
alpha (glucagon) beta (insulin)
31
pancreatic acini
secrete into digestive tract
32
insulin
increase rate of glucose transport, utilisation and conversion to glycogen increase aa absorption and protein synthesis increase trig synthesis
33
glucagon
increase break down of glycogen to glucose, fatty acids and release of glucose
34
diabetes mellitus
high blood glucose (hyperglycaemia)
35
results of diabetes if untreated
kidney damage retinal damage periphery nerve damage
36
type I diabetes
insulin dependent injection inadequate insulin produced
37
type II diabetes
tissue not responsive to insulin
38
patterns of hormonal interaction
antagonistic (opposing effects) synergistic (addictive) permissive (one needed for another to effect) integrative (diff but complementary results)
39
antagonistic hormones
PTH and Calcitonin
40
synergistic hormones
GH and glucocorticoids
41
phases of general adaptation syndrome
alarm phase resistance phase exhaustion phase
42
alarm phase
sympathetic activation and epinephrine and norepinephrine increase hr and energy usage
43
resistance phase
GH and glucocorticoids mineralocorticoids and ADH lipids and aa released peripheral tissue breaks down lipids liver synthesise glucose = high blood conc loss of salts and water
44
exhaustion phase
exhaustion of lipids reserves can't produce glucocorticoids failure of electrolyte balance damage to vital organs