Endocrine/Pancreas - Exam 3 Flashcards

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1
Q

exocrine

A

majority, acinar cells and duct cells, GI function, secrete enzymes into the lumen of the duodenum

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2
Q

endocrine

A

islets of langerhans

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3
Q

endocrine cell types

A

beta, alpha, delta, F

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4
Q

alpha cell

A

glucagon

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5
Q

delta cell

A

somatostatin - inhibitor of insulin secretion

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6
Q

beta cell

A

insulin

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7
Q

F cell

A

pancreatic polypeptide

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8
Q

insulin secreted in response to

A

hyperglycemia, synthesized as a larger molecule inside Golgi and packaged into secretory granules awing secretion, release contents via exocytosis, then goes to circulation

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9
Q

GLUT2

A

allows insulin to diffuse freely into the cell, make ATP, voltage gated calcium channels, insulin exocytosis, binds to receptor tyrosine kinase

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10
Q

increase in blood glucose =

A

insulin secretion

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11
Q

insulin sensitive tissues

A

liver, muscle, fat, GLUT4

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12
Q

liver insulin sensitive

A

increase glycogen synthesis, increase lipogenesis

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13
Q

muscle insulin sensitive

A

increase glucose transport, increase glycogen synthesis, increase amino acid uptake, increase protein synthesis

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14
Q

fat insulin sensitive

A

increase glucose transport, increase glycogen synthesis, increase lipogenesis

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15
Q

counter regulatory hormones

A

glucagon (alpha), epinephrine (medulla), cortisol (cortex), growth hormone (adenohypophysis)

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