Cell Junctions - Exam 2

Question 1

epithelial tissues (tightly bound) found

Answer 1

lining of gut, covering of skin

Question 2

cell-cell junction main function

Answer 2

direct attachments between cells

Question 3

cell-matrix junction main function

Answer 3

cytoskeletal, anchored, link basal lamina

Question 4

connective tissues found

Answer 4

bone/tendon

Question 5

connective tissues characteristics

Answer 5

cells sparsely distributed, direct attachment rare, cell, matrix junctions present, bear mechanical stress

Question 6

tight junctions function, characteristics, & where found

Answer 6

seals gaps, selectively permeable, apical, intestinal mucosa, bladder

Question 7

Celiac Disease & Crohn’s Disease caused by

Answer 7

leaky tight junctions

Question 8

cell-cell anchoring junctions use what enzyme

Answer 8

cadherins (calcium dependent adhesion)

Question 9

adherens characteristics & function

Answer 9

“zonula”, “intermediate junction”, “belt”
developing tissue & tissue remodeling
connects actin filaments

Question 10

where are adherens junctions found

Answer 10

basal, epi cells, cardiac muscle, fibroblasts

Question 11

desmosome characteristics & function

Answer 11

“macula”
anchorage & strength
connects intermediate filaments

Question 12

where are desmosome junctions found

Answer 12

skin, intestines, stomach, bladder (stretch)

Question 13

gap junctions function

Answer 13

passage of small H2O soluble molecules like ion & glucose (without using plasma membrane)

Question 14

where are gap junctions found

Answer 14

connective/epi tissue, cardiac muscle, neurons (electricity)

Question 15

cell-matrix anchoring junctions function

Answer 15

sense & respond to mechanical forces using inegrins

Question 16

integrins

Answer 16

cell-cell & cell-matrix

Question 17

actin-linked junctions bind

Answer 17

“focal adhesion”; actin filaments to ECM

Question 18

examples of actin-linked junctions

Answer 18

fibroblasts to culture, muscle cells to tendons

Question 19

hemidesmosomes bind

Answer 19

intermediate filaments to ECM

Question 20

examples of hemidesmosome junctions

Answer 20

integrins, epi cells to basal lamina