Endocrine Glands And Cranial Base Flashcards

1
Q

What is the ossification of the Neurocranium?

A

Skull cap and skull base
Chondrocranium (cranial base) = endochondral ossification
Membranous neurocranium = intramembranous ossification

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2
Q

What bones make up the skull base?

A

Ethmoid, sphenoid, occipital, paired frontal, paired temporal

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3
Q

What are bones anterior to the sella turcica derived from (of the skull base)?

A

Bones anterior to sella turcica are derived from neural crest cells

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4
Q

What are bones behind/posterior to the sella turcica derived from (of the skull base)?

A

Bones behind the sella turcica are derived from paraxial mesoderm

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5
Q

How is the anterior pituitary gland developed embryonically?

A

Diverticulum develops from the embryonic buccal cabvity. It has finger-like projections going upwards, lodging itself around the bones of the Chondrocranium as they form around it. This Rathke’s pouch becomes the anterior pit gland.

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6
Q

How is the posterior pituitary gland developed embryonically?

A

Finger-like downward projection from the diencephalon. This becomes the posterior pit gland.

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7
Q

How do the anterior and posterior parts form the pituitary gland?

A

When both upward and downward projections meet, they come together at around the level of the 3rd ventricle, forming the pituitary gland.

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8
Q

What bones are found in each cranial fossa?

A

Anterior - upper surface of ethmoid bones, orbital plate of frontal bone, lesser wings of sphenoid
Middle - sphenoid, temporal
Posterior - occipital

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9
Q

Main features of ethmoid bone

A

Cribiform plate where olfactory nerves come through
Crista galli, a continuation of the perpendicular plate and attachment for falx cerebri
Ethmoidal air cells, collecting to form the ethmoidal bulla

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10
Q

What can happen when the ethmoid bone fractures?

A

Tearing of the meninges from the crista galli
Anosmia
CSF rhinorrhoea - leaking through the subarachnoid space through the nose.

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11
Q

How do you diagnose CSF rhinorrhoea?

A

If product is collected it forms a chromatographic separation of blood and CSF.

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12
Q

Main features of the sphenoid

A

Body
Greater and lesser wings
Pterygoid processes downwardly projecting
Dorsum sellae
Posterior and anterior clinoid processes - important for attachment of meninges
Sella turcica holding pituitary gland in hypophyseal fossa by the meninges

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13
Q

What does the diaphragma sellae allow?

A

The attachment of the meninges around the sphenoid body seals off the area to allow the pituitary gland to sit in place through the diaphragma sella. There is a puncture in the membrane allowing pituitary stock to emerge through that.

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14
Q

Main features of temporal

A

Petrous part (seen from inside), squamous part, mastoid part, tympanic part (opening into external auditory meatus), styloid process, zygomatic process, internal acoustic meatus

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15
Q

Where do the meninges attach to the temporal bone?

A

Petrous part

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16
Q

What are fissures usually filled with?

A

Soft tissues
Only demonstrable in dry bones

17
Q

Key fissures of the skull base

A

Petrosphenoidal fissure
Petrooccipital fissure

18
Q

Key sutures of the skull base

A

Sphenosquamous suture
Occipitomastoid sutures

19
Q

What is the outer part of the foramen lacerum covered by?

A

A cartilaginous plate

20
Q

How does the foramen lacerum relate to the carotid canal?

A

ICA enters region of the cavernous sinus through the petrous temporal bone through the carotid canal, and exits via the foramen lacerum.

21
Q

What does the ICA bring with it through the foramen lacerum and carotid canal?

A

Sympathetic fibres ride on the ICA and use it as a sympathetic drive to the head. Comes in as a blood vessels carrying sympathetic nerves, which come together to form the deep petrosal nerve.

22
Q

Describe how fibres from the pterygopalatine ganglion become the greater petrosal nerve

A

Pterygopalatine ganglion receives preganglionic parasympathetic fibres from the greater petrosal nerve, starting from the brain and passing without terminating through the geniculate ganglion. Fibres eventually become the greater petrosal nerve - parasympathetic fibres which terminate in the pterygopalatine fossa.

23
Q

How does the vidian nerve form?

A

Nerve of vidian canal/pterygoid canal
Forms by the confluence of the greater petrosal nerve and the deep petrosal nerve

24
Q

What is the main point of weakness of the cranial base?

A

Line from the pterygopalatine fossa all the way to the jugular foramen. High energy image causes damage to the cranial base here.

25
Q

What can fractures of the cranial base cause?

A

Damage and haematoma
Raccoon eyes = presentation of bilateral orbital ecchymosis
CSF rhinorrhoea
Maxillofacial trauma

26
Q

Features of the cavernous sinus

A

ICA
CNIII, CNIV, CNV1, CNV2
CNVI (in the middle)
Pituitary gland