Endocrine (Chapter 16) Flashcards
Secretes hormones into the bloodstream
Endocrine System
A chemical messenger secreted into the blood that triggers changes with in its target cells
Hormones
Master gland, takes stimulation from the hypothalamus (control center) and directs it to all the other endocrine glands
Pituitary Gland
Regulates metabolism through the hormones (T3 and T4)
Thyroid Gland
Regulates the body blood calcium levels through the parathyroid hormone. (muscle contraction, bone growth,etc)
Parathyroid Gland
Is where the adrenal corticosteroids (cortisol and aldosterone) are made,
Adrenal Cortex (outer)
Is where the adrenal catecholamines (epinephrine and norepinephrine) are made, fight or flight hormones.
Adrenal Medulla (inner)
Secretes sex hormones progesterone and estrogen in females and testosterone in males.
Gonads (Ovaries and Testes)
Stimulates blood sugar with the hormones insulin and glucagon
Pancreas
Function at the cell that makes them
Autocrine hormones
Function regionally.
Paracrine hormones
Function at a distance.
Endocrine hormones
Small anteroinferior portion of the diencephalon of the brain that transports neural signals from the brain to the pituitary gland.
Hypothalamus
Also called the hypophysis
Pituitary Gland
Connects the hypothalamus to the pituitary gland
Infundibulum
Also called adenohypophysis
Anterior pituitary gland
Also called neurohypophysis
Posterior pituitary gland
A hypothalamic hormone that control water balance
Antidiuretic Hormone (ADH)
A hypothalamic hormone that support reproduction and milk release
Oxytocin
Stimulate or inhibit the release of hormones from the anterior pituitary gland.
Releasing and Inhibiting Hormones
Anterior pituitary hormone that stimulates the production and release of thyroid hormone and growth of the thyroid gland.
Thyroid-stimulating hormone (TSH)
Anterior pituitary hormone that is released by the adrenal cortex that stimulates the production of mostly glucocorticoids from the adrenal cortex.
Adrenocorticotropic hormone (ACTH)
Hormones produced by the anterior pituitary gland that stimulates reproductive functions in males and females.
Luteinizing Hormone (LH)
Hormone produced by the anterior pituitary gland that stimulates reproductive functions in males and females.
Follicle-stimulating Hormone
A hormone produced by the anterior pituitary gland that stimulates the growth of the mammary gland, initial of milk production after childbirth, and the maintenance of milk production for the duration of breastfeeding.
Prolactin (PRL)
Stimulate male and female gonads to produce testosterone in males and estrogen and progesterone in females
Gonadotropin-releasing hormone (GnRH)
A hormone produced by the anterior pituitary gland that promotes fat breakdown and gluconeogenesis, also stimulates the release of insulin-like growth factor, which promotes growth and protein synthesis.
Growth hormone (GH)
Connects the right and left lobes of the thyroid gland
Isthmus
The spheres located in the thyroid gland
Thyroid follicles
The protein-rich, gelatinous material that fills the interior of the thyroid follicle.
Colloid
Thyroid hormones that regulates metabolism and thermoregulation, promotion of growth and development, and synergism with the sympathetic nervous system.
Triiodothyronine and Thyroxine (T3 and T4)
Triiodothyronine (T3) and Thyroxine (T4)
What are the two forms of thyroid hormones?
Overproduction of thyroid hormone
Hyperthyroidism (Graves Disease)
Underproduction of thyroid hormone
Hypothyroidism
A hormone produced by the parathyroid gland that increases the blood calcium ion concentration in the extra cellular fluid.
Parathyroid Hormone (PTH)
A hormone produced by the parafollicular cells of the thyroid gland that decreases the blood calcium ion concentration
Calcitonin
What are the two regions of the adrenal glands?
Adrenal cortex and Adrenal medulla
What are the three zones of the adrenal cortex?
Zona glomerulosa (outer) -densely packed cells Zona fasciculata (middle) -cells stacked in columns Zona reticularis (inner) -arranged loosely in clusters
A hormone produced by the adrenal cortex that increases the reabsorption of sodium ions (and indirectly) water from the distal tube, as well as the secretion of potassium and hydrogen ions.
Aldosterone
The main glucocorticoid produced by the adrenal cortex, stimulates gluconeogenesis as well as fat and protein breakdown and inhibits the inflammatory response.
Cortisol (hydrocortisone)
Produced in the Zona fasciculata and Zona reticularis, and their main role is to help mediate the body’s response to stress (regulating the concentration of blood glucose)
Glucocorticoids
A series of changes that maintains homeostasis when the body is faced with a stressor (exercise, emotional excitement, being chased by an animal, etc)
Stress Response
Sex hormones that affect the reproductive organs, gonads, and multiple other tissues.
Androgenic hormones
What’s are the two groups of cells in the pancreas?
Pancreatic islets (endocrine cells) and Islets of Langerhans (exocrine cells)
What are the three main cell types of Pancreatic Islets?
- alpha cells- secretes hormone glucagon
- beta cells- secretes hormone insulin
- delta cells- secretes hormone somatostatin
Increases the levels of glucose mad other metabolic fuels in the blood
Glucagon
Decreases the levels of glucose in the blood
Insulin
When insulin levels rise to high and blood glucose levels drops
Hypoglycemia
Decreased levels of insulin that cause the blood glucose levels to become elevated
Hyperglycemia
Caused by the destruction of the insulin-producing beta cells in the pancreas by the immune system
Type 1 diabetes mellitus
The beta cells in the pancreas do not respond to normal increases in blood glucose, and other target cells are less responsive to insulin
Type 2 diabetes mellitus
A hormone produced by the pineal gland that regulates the sleep and wake cycle
Melatonin
The site of maturation of the white blood cells (leukocytes) called T lymphocytes
Thymus
What to hormones does the thymus secretes?
Thymosin and Thymopoietin
Responsible for the production of gamete (sperm and ova)
Gonads
What is the name of the hormone produced by the testes?
Testosterone
What is the name of the hormone produced by the ovaries?
Estrogen and Progesterone
What are the two hormones produced by the pancreas?
Glucagon and Insulin
A hormone produced by adipocytes that promotes satiety (feelings of fullness after eating)
Leptin
A hormone produced by cells of the heart that triggers the excretion of sodium ions (and indirectly water) from the renal tubule of the kidneys
Atrial natriuretic peptide (ANP)
The hormone produced by the kidneys that increases the rate of the erythrocyte production and decreases the time it takes for them to mature
Erythropoietin (EPO)
An enzyme produced by JG cells in response to a decline systemic blood pressure or sympathetic nervous system stimulation
Renin
Clusters of cells between thyroid follicles that produce the hormone calcitonin
Parafollicular cells
Hormone secreting cells of the parathyroid gland that produce the parathyroid hormone
Chief cells
Hypersecretion of GH before closure of the epiphyseal plates
Gigantism
Hyposecretion of GH prior to closure of the epiphyseal plates
Pituitary dwarfism
An abnormal lack of ADH secretion or activity
Diabetes insipidus
Signals consist of a chemical secreted by cells into the extracellular fluid to nearby but different types of cells
Paracrine signals
A chemical secreted by cells into the interstitial fluid elicits effects from the same cell or cell type
Autocrine signals
A hormone produced largely by the liver in response to the growth hormone, stimulates protein synthesis and cell division
Insulin-like growth factor (IGF)