Endocrine anatomy Flashcards

1
Q

How many endocrine diseases diagnosed in UK

A

3.5 million

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2
Q

Why are endocrine around large blood vessels

A

To maintain good supply of blood

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3
Q

What are cushings like symptoms

A
  • Fat deposits developing in face
  • Thinning of skin
  • Weight gain
  • Reddish purple stretch marks
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4
Q

Where is the pituitary gland found

A

Centre of sphenoid bone- sella turcica

Hangs on hypothalamus

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5
Q

What can be seen posteriorly and anteriorly of hypothalamus

A

Mammaralary glands

Optic chiasm

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6
Q

What connects pituitary gland to hypothalamus

A

Infundibulum

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7
Q

Which lobe of the pituitary is an extension of the hypothalamus

A

Posterior lobe

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8
Q

Which lobe of the pituitary is more gland like

A

Anterior lobe

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9
Q

What is secreted by anterior lobe

A
ACTH
TSH
LG
TSH
Prolactin
growth hormone
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10
Q

What is secreted by posterior lobe

A

ADH

Oxytocin

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11
Q

Where do cell bodies collect in the hypothalamus

A
  • Supraoptic nuclei

- paraventricular nuclei

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12
Q

What do the axons from the supraoptic nuclei transport

A

ADH

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13
Q

Where does the posterior pituitary secrete its hormones

A

Into the capillary bed

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14
Q

What do the axons travelling from the paraventricular nuclei transport

A

Oxytocin

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15
Q

Which artery runs either side of the pituitary gland

A

Internal carotid artery

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16
Q

What branch is given off by the ICA to supply hypothalamus and pituitary gland

A

Superior hypophyseal artery

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17
Q

What capillary bed does the superior hypophyseal artery break up into within the hypothalamus

A

Primary plexus

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18
Q

Where does blood from the anterior pituitary gland drain into

A

Hypophyseal portal vein
Secondary plexus
Efferent hypophyseal veins
Cavernous sinus

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19
Q

What happens if blood coming into hypothalamus has low levels of T3 and T4

A

Releases thyrotrophin releasing hormone into the primary plexus
Stimulates TSH release
Via efferent hypophyseal into general circulation

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20
Q

Where does ACTH act

A

Adrenal glands to release cortisol

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21
Q

What would be the visual defect as a result of pituitary adenoma

A

Bitemporal hemianopia (optic chiasm lesion)

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22
Q

What runs through cavernous sinus

A
ICA
Occulomotor nerve
Trochlear
V1 and V2 and trigeminal
Abducens
23
Q

Why does somebody with pituitary adenoma have cushings like symptoms

A

Excessive hormone production

24
Q

Why do people with pituitary adenoma have progressive opthalmoegia

A

Crushing contents of cavernous sinus

25
Which lobe of pituitary lobe most commonly gets tumour
Anterior lobe
26
Treatment for pituitary tumour
Surgery to remove tumour and leave at least some of the normal pituitary gland
27
What happens if there is excess of LH/ FSH
- rare | - irregular menstrual cycles or decreased sex interest
28
What happens if there is excess growth hormones
giantism in kids | acromegaly in adults
29
What happens if there is excess TSH
Hyperthyroidism weight loss rapid heart rate tremors
30
What happens if there is excess ACTH
Excess cortisol | Cushings
31
What are the 2 parts of the adrenal gland
Adrenal cortex and adrenal medulla
32
What is secreted from the adrenal cortex
Aldosterone Cortisol Androgens
33
What is secreted from adrenal medulla
Adrenaline | Noradrenaline
34
What are the 3 zones of the adrenal cortex
Zona glomerulosa Zona fasciculara Zona reticularis (innermost)
35
Which zone of the adrenal cortex secrets androgens
Reticularis
36
Which zone of the adrenal cortex secretes glucocorticoids
Fasciularis
37
Which area of the adrenal gland secretes aldosterone
Glomerulosa
38
Where are the adrenal glands located
Superomedial aspects of kidneys and crura of diaphragm | In perineal fat
39
What arteries supply adrenal glands
Superior suprarenal Middle suprarenal Inferior suparenal
40
What is the largest artery above suprarenal glands? What vessels comes off of it
Inferior phrenic artery | The superior suprarenal arteries (6-8 of them)
41
What does middle suprarenal artery come from
Abdominal aorta
42
What does the inferior suprarenal artery come from
Renal artery
43
Where does the right and the left adrenal gland drain blood to
``` Right= IVC Left= left renal vein ```
44
Where does the thyrohoid muscle go
GOing between hyoid bone and thyroid
45
Where does sternothyroid go
Sternum and thyroid cartilage
46
Which are the 2 deeper infrahyoid muscles
Thyrohoid and sternothyroid
47
Where does sternohyoid go
Sternum to hyoid
48
Where does omohyoid go
From hyoid to shoulder
49
What happens if infrahyoid muscles contract
Hyoid goes down
50
What level does thyroid gland lie
C5-T1
51
Where does thyroid gland originate
Part of tongue
52
Does internal carotid artery branch in the neck
Nah mush
53
What arteries supply yhtyoid
Superior and inferior thyroid arteries
54
What structures surrounding the thyroid gland must a surgeon avoid during thyroidectomy
Recurrent laryngeal nerve---> dysphonia Parathyroid glands---> tetany Thyroid ima artery-->