Endocrine Flashcards
Pituitary Dwarfism
Risks/Causes: Injury or trauma to pituitary gland, genetics, tumor in pituitary gland, radiation treatment to the head
Prevention: Prevent injury or trauma to the head
Gigantism
Causes: Benign tumor that leads to excessive secretion of GH
Prevention: Not possible
Acromegaly
Causes: Benign tumor that leads to excessive secretion of GH
Prevention: Early treatment
Diabetes Insipidus(DI)
Risks: Head injury, brain surgery, kidney disease, pregnancy, medications(lithium, amphotericin B, demeclocycline)
Causes: Central DI(damage to pituitary gland from surgery, tumor and illness such as meningitis, inflammation or head injury), Nephrogenic DI(defect in kidney tubules, kidneys can’t respond to ADH, use of certain drugs such as lithium and demeclocycline)
Hypothyroidism
Risks: Female, age over 50, having an autoimmune disorder, having a close relative with thyroid disease or an autoimmune disease, use of radioactive iodine, radiation to the head or neck, surgical removal of the thyroid gland, treatment with antithyroid medication, pregnancy, some medications(lithium, interferon)
Causes: Autoimmune diseases(Hashimoto’s), surgery to remove all or part of the thyroid, radiation, treatment of hyperthyroidism, certain medications(lithium, interferon)
Congenital Hypothyroidism
Causes: Hypoplasia(underdevelopment), aplasia(absence of development), failure of the thyroid gland to migrate to its normal anatomical position, iodine deficiency, ingestion of antithyroid medication during pregnancy
Hyperthyroidism(Grave’s Disease)
Risks: Female, family history, stress and smoking
Simple Goiter
Risks: Being female, over age 40, having a family history of goiter
Causes: Iodine deficiency, eating a large amount of goiter producing foods(soy, peanuts, beaches, spinach, turnips, cabbage, brussel sprouts, seaweed), certain medications(immunosuppressants, antiretrovirals, lithium), idiopathic
Thyroid Cancer
Risks: Female, a diet low in iodine, and exposure to radiation
Hyperparathyroidism
Risks: Over the age of 50 years, women, postmenopausal, chronic vitamin D deficiency, neck area radiation, lithium therapy
Causes: Benign tumors of parathyroid, causing over secretion of PTH
Hypoparathyroidism
Risks: Damage to the glands from heavy metals(copper or iron), immune disorders(Addison’s), family history, some infections, surgical removal of thyroid
Hypoadrenalism
Causes: May result from any disease process that damages the entire adrenal cortex, autoimmune processes, infectious diseases(tuberculosis), fungal disease, opportunistic infections associated with aids, certain cancers, hemorrhage of the adrenal gland secondary to anticoagulation medication
Acute Adrenal Insufficiency
Risks/Causes: Infection, trauma, severe physical stress such as surgery
Hyperadrenalism(Cushing’s Syndrome)
Risks: Adrenal tumor, corticosteroid therapy
Causes: Benign pituitary tumor
Prevention: Preventable is related to cortisone replacement therapy by carefully monitoring signs and symptoms
Hyperadrenalism(Conn’s Syndrome)
Risks: None known, women are twice as likely as men, and the incidence increases with age
Causes: Results from a benign tumor most of the time