Endo week 3 Flashcards

1
Q

magnocellular neurons release what kind of hormone from where?

A

magnocellular neurons release what kind of hormone from where?

Answer:
oxytocin and ADH from posterior pituitary

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2
Q

parvocellular neurons release what kind of hormone from where?

A

parvocellular neurons release what kind of hormone from where?

Answer: hypothalamus releases inhibitory and releasing hormones which act on Anterior pituitary

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3
Q

the pituitary gland lies in a bony cavity called the?

A

the pituitary gland lies in a bony cavity called the?

Answer: Sella Turcica

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4
Q

what is the difference between tropic and tropHic hormones?

A

what is the difference between tropic and tropHic hormones?

Answer:
- tropic = hormone regulates hormone (exp: CRH, GnRH)

  • tropHic = hormone regulates growth & development
    (exp: ACTH, TSH, FSH)
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5
Q

which nucleus secrete ADH and OT

A

which nucleus secrete ADH and OT

Answer:
paraventricular nucleus = Oxytocin
supraoptic nucleus = ADH

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6
Q

parturition reflex and milk let down reflexes are an example of _____________ reflex.

A

parturition reflex and milk let down reflexes are an example of ___neuroendocrine___ reflex

because: part of the reflex is neural and part is endocrine

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7
Q

hypophysiotropic hormones are secreted from what and regulate what?

A

hypophysiotropic hormones are secreted from what and regulate what?

Answer: hypothalamus secreted them and they regulate the release of hormones from the anterior pituitary.

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8
Q

CRH uses what kind of secondary messenger?

A

CRH uses what kind of secondary messenger?

Answer:
GPCR —> cAMP —> Protein Kinase A –> increase Ca2+ –> ACTH released

CRH acts on corticotrophs to increase synthesis and secretion of ACTH

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9
Q

TRH uses what kind of secondary messenger?

A

TRH uses what kind of secondary messenger?

Answer:
GPCR –>IP3 –>increase Ca2+ –> TSH released

TRH acts on thyrotrophs to increase synthesis & secretion of TSH

TRH also stimulates lactotrophs to release Prolactin

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10
Q

GHRH uses what kind of secondary messenger?

A

GHRH uses what kind of secondary messenger?

Answer:
GPCR –> cAMP –> Protein Kinase A –>increase Ca2+ –> GH released.

GHRH and GHIH(SS) work on somatotrophs

GHRH increase synthesis and secretion of GH

SS inhibit secretion of GH and TSH

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11
Q

GnRH uses what kind of secondary messenger?

A

GnRH uses what kind of secondary messenger?

Answer:
GPCR –> IP3 –>increase Ca2+ –> FSH and LH

GnRH acts on gonadotrophs to increase synthesis and secretion of FSH and LH

GnRH is released in a pulsatile manner.

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12
Q

what is the precursor to ADH and what are the other chemicals released with ADH ?

A

what is the precursor to ADH and what are the other chemicals released with ADH ?

Answer:
prepropressophysin -> ADH + neurophysin II + glycopeptid

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13
Q

what is the precursor to Oxytocin and what are the other chemicals released with Oxytocin ?

A

what is the precursor to Oxytocin and what are the other chemicals released with Oxytocin ?

Answer:
prepro-oxyphisin –> Oxytocin + neurophysin I

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