ENDO VS. EXO TOXINS Flashcards
bacterial source: exotoxins
G+ and G-
bacterial source: endotoxins
G- only
location in the bacterium: exotoxins
synthesized in the cytoplasm, may or may not be secreted
location in the bacterium: endotoxins
outer membrane, characteristic of G- cell wall
chemical nature: exotoxins
protein
chemical nature: endotoxins
the lipid A component of lipopolysaccharide
ability to form a toxoid: exotoxins
generally, yes
ability to form a toxoid: endotoxins
no
heat stability: exotoxins
generally inactivated by heat
heat stability: endotoxins
heat stable
mechanism: exotoxins
distinct toxic mechanism for each
mechanism: endotoxins
innate immune response; systemic response can lead to septic shock and disseminated intravascular coagulation
toxicity: exotoxins
generally very potent; some are among the most toxic known toxins
toxicity: endotoxins
small amounts in a localized area lead to an appropriate immune response that clears an infection; systemic distribution can be deadly
G+ and G-
exotoxins
G- only
endotoxins
synthesized in the cytoplasm
exotoxins
may or may not be secreted
exotoxins
found in the outer membrane
endotoxins
characteristic of G- cell wall
endotoxin
protein
exotoxin
lipid A component of lipopolysaccharide
endotoxin
generally able to form a toxoid
exotoxin
unable to form a toxoid
endotoxin
