ENDO VS. EXO TOXINS Flashcards

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1
Q

bacterial source: exotoxins

A

G+ and G-

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2
Q

bacterial source: endotoxins

A

G- only

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3
Q

location in the bacterium: exotoxins

A

synthesized in the cytoplasm, may or may not be secreted

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4
Q

location in the bacterium: endotoxins

A

outer membrane, characteristic of G- cell wall

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5
Q

chemical nature: exotoxins

A

protein

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6
Q

chemical nature: endotoxins

A

the lipid A component of lipopolysaccharide

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7
Q

ability to form a toxoid: exotoxins

A

generally, yes

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8
Q

ability to form a toxoid: endotoxins

A

no

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9
Q

heat stability: exotoxins

A

generally inactivated by heat

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10
Q

heat stability: endotoxins

A

heat stable

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11
Q

mechanism: exotoxins

A

distinct toxic mechanism for each

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12
Q

mechanism: endotoxins

A

innate immune response; systemic response can lead to septic shock and disseminated intravascular coagulation

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13
Q

toxicity: exotoxins

A

generally very potent; some are among the most toxic known toxins

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14
Q

toxicity: endotoxins

A

small amounts in a localized area lead to an appropriate immune response that clears an infection; systemic distribution can be deadly

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15
Q

G+ and G-

A

exotoxins

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16
Q

G- only

A

endotoxins

17
Q

synthesized in the cytoplasm

A

exotoxins

18
Q

may or may not be secreted

A

exotoxins

19
Q

found in the outer membrane

A

endotoxins

20
Q

characteristic of G- cell wall

A

endotoxin

21
Q

protein

A

exotoxin

22
Q

lipid A component of lipopolysaccharide

A

endotoxin

23
Q

generally able to form a toxoid

A

exotoxin

24
Q

unable to form a toxoid

A

endotoxin

25
Q

heat-stable

A

endotoxin

26
Q

generally inactivated by heat

A

exotoxin

27
Q

distinct toxic mechanism for each

A

exotoxin

28
Q

innate immune response

A

endotoxin

29
Q

systemic response can lead to septic shock and disseminated intravascular coagulation

A

endotoxin

30
Q

generally very potent

A

exotoxin

31
Q

among the most toxic know toxins

A

exotoxin

32
Q

small amount in localized areas trigger an appropriate immune response to clear an infection

A

endotoxin

33
Q

systemic distribution can be deadly

A

endotoxin