Endo S Flashcards
Second messenger system of the body
endocrine system
Endocrine system use ___ that are released into the blood
chemical messages (hormones)
Uses chemical messages (hormones)
that are released into the blood
endocrine system
produced by specialized cells
Hormones
control several major
processes
Hormones
Hormones control several major
processes (5)
Reproduction
Growth and development
Mobilization of body defenses
Maintenance of much of homeostasis
Regulation of metabolism
Hormones are produced by
specialized cells
Cells secrete hormones into
extracellular fluids
Blood transfers hormones to
target sites
regulate the activity of
other cells
hormones
Amino acid based hormones (3)
Proteins
Peptides
Amines
Steroids made from
cholesterol
Prostaglandins made from highly
active lipids
made from highly active lipids
Prostaglandins
made from cholesterol
Steroids
transfers hormones to target sites
Blood
Hormones affect only (2)
certain tissues or
organs (target cells or organs)
binding influences the working of the cells
Hormone
can alter cellular activity
byincreasing or decreasing the rate of a
normal metabolic process rather than
by stimulating performance of a new one
Hormones
Hormones can alter cellular activity
by ___ or ___the rate of a
normal metabolic process rather than
by ___ performance of a new one
increasing or decreasing
stimulating
Hormone levels in the blood are
maintained by
negative feedback
typically act through second-messenger systems
amino-acid-based hormones
Endocrine glands are activated by other
hormones
___ or ___ in theblood triggers the release of more
hormone
stimulus or low hormone levels
Steroid hormones can act through either
-direct gene activation
-second-messenger systems
Endocrine glands are activated by other hormones
Hormonal Stimuli of Endocrine
Glands
Changing blood levels of certain ions stimulate hormone release
Humoral Stimuli of Endocrine
Glands
Changing blood levels of certain ions stimulate___
hormone release
nerve fibers stimulate hormone release,
and the endocrine cells are said to respond to neural stimuli.
Neural Stimuli of Endocrine Glands
_____ stimulate hormone release,
and the endocrine cells are said to respond to __
nerve fibers
neural stimuli
(3) Stimuli of Endocrine Glands
Hormonal Stimuli
Humoral Stimuli
Neural Stimuli
Location of Major Endocrine Organs (10)
Pineal Gland
Hypothalamus
Pituitary Gland
Thyroid Gland
Parathyroid Gland
Thymus Gland
Pancreas
Ovary
Testis
Size of pituitary gland
grape
Pituitary Gland hangs by a stalk from the
hypothalamus
Pituitary Gland protected by the
sphenoid bone
How many hormones does Anterior Pituitary have
6
Pituitary Gland: two functional lobes
Anterior pituitary-glandular tissue
Posterior pituitary-nervous tissue
Anterior pituitary-
Posterior pituitary-
Anterior pituitary- glandular tissue
Posterior pituitary-nervous tissue
-
Two affect non endocrine targets
Four stimulate other endocrine glands
(tropic
___ affect non endocrine targets
___ other endocrine glands
(tropic hormone)
Two hormones
Four stimulate
Four hormone that stimulate other endocrine glands
tropic hormones
Characteristics of all anterior pituitary
hormones (3)
Proteins (or peptides)
Act through second messenger systems
Regulated by hormonal stimuli, mostly
negative feedback
Hormones of the Anterior Pituitary is regulated by
hormonal stimula
Anterior pituitary hormones act through second
second messenger systems
Anterior Pituitary is regulated by hormonal stimuli, mostly
negative feedback
Hormones of the Anterior Pituitary
Growth hormone-
Prolaction-
Follicle-Stimulating Hormone and Luteinizing hormone-
Thyrotropic hormone-
Adrenocorticotropic hormone-
Hormones of the Anterior Pituitary
Growth hormone- Bones and muscle
Prolaction-mammary gland
Follicle-Stimulating Hormone and Luteinizing hormone- Testes and Ovaries
Thyrotropic hormone- Thyroid
Adrenocorticotropic hormone- Adrenal Cortex
Hypothalamus releasing hormone in
portal circulation
Hormones of the Anterior Pituitary
- Bones and muscle
- Testes and Ovaries
- Thyroid
- Adrenal Cortex
Hormones of the Anterior Pituitary
Growth hormone- Bones and muscle
Prolaction-mammary gland
Follicle-Stimulating Hormone and Luteinizing hormone- Testes and Ovaries
Thyrotropic hormone- Thyroid
Adrenocorticotropic hormone- Adrenal Cortex
General metabolic hormone
Growth hormone
Growth Hormone (GH)
Major effects are directed to growth of (2)
skeletal muscles and long bones
Causes amino acids to be built into
proteins
Growth Hormone
Stimulates and maintains milk production
following childbirth
Prolactin (PRL)
Growth hormone causes amino acids to be built into
proteins
Causes fats to be broken down for a
source of energy
Growth Hormone
Prolactin (PRL)- Function in ___ is unknown
males
Regulates endocrine activity of the adrenal
cortex
Adrenocorticotropic hormone (ACTH)
Thyroid stimulating hormone (TSH)
Influences growth and activity of the thyroid
Regulate hormonal activity of the gonads
Gonadotropic hormones
Stimulates follicle development in
ovaries
Stimulates sperm development in
testes
Follicle stimulating hormone (FSH)
Triggers ovulation
Luteinizing hormone (LH)
Gonadotropic hormones (2)
Follicle stimulating hormone (FSH)
Luteinizing hormone (LH)
Stimulates testosterone production in
males
Referred to as
interstitial cell stimulating hormone (ICSH)
Causes ruptured follicle to become the
corpus luteum
Luteinizing hormone (LH)
Stimulates testosterone production in
males
Luteinizing hormone (LH)
Stimulates contractions of the uterus during labor
Oxytocin
Causes milk ejection
Oxytocin
Can inhibit urine production
Antidiuretic hormone (ADH)
In large amounts, causes vasoconstriction
leading to increased blood pressure
(vasopressin)
Antidiuretic hormone (ADH)
increased blood pressure
(vasopressin)
Found at the base of the throat
Thyroid Gland
Thyroid Hormone composed of two active iodine containing hormones
Thyroxine (T 4 )
Triiodothyronine (T3)
Thyroid Glands consists of
two lobes and a connecting isthmus
Major metabolic hormone
Thyroid Hormone
Thyroid Gland produces two hormones
Thyroid hormone
Calcitonin
Antagonistic to parathyroid hormone
Calcitonin
Produced by C (parafollicular) cells
Calcitonin
Calcitonin is produced by
C (parafollicular) cells
Decreases blood calcium levels by
causing its deposition on bone
Calcitonin
Tiny masses on the posterior of the
thyroid
Parathyroid Glands
Triiodothyronine (T 3 ) conversion of __ at
___
T 4
target tissues
Parathyroid Glands secrete
parathyroid hormone
Thyroxine (T 4 ) secreted by
thyroid follicles
parathyroid hormone raises ___ in the blood
Calcium levels
Stimulate osterclasts to remove calcium
from bone
parathyroid hormone
Stimulate the kidneys and intestine to
absorb more calcium
parathyroid hormone
Adrenal Glands has two gland
-their function
Cortex outer glandular region in three
layers
Medulla inner neural tissue region
Glucocorticoids produced in the middle layer of the
adrenal cortex
Sits on top of the kidneys
Adrenal Glands
(including cortisone and cortisol)
Glucocorticoids
Hormones of the Adrenal Cortex
Glucocorticoids
Sex hormones
Promote normal cell metabolism
Glucocorticoids
Help resist long term stressors
Glucocorticoids
Produced in the inner layer of the adrenal
cortex
sex hormones
Androgens (male) and some estrogen
(female)
Sex hormones
Released in response to increased blood
levels of ACTH
Glucocorticoids
These hormones prepare the body to
deal with short term stress
Hormones of the Adrenal Medulla
The pancreas is a
mixed gland
Short term stress response (1)
Long term stress response (2)
Short term stress response
-Catecholamines
Long term stress response
-Mineralocorticoids
-Glucocorticoids
Hormones of the Adrenal Medulla produces two similar hormones
(catecholoamine)
Epinephrine
Norepinephrine
allows glucose to cross plasma membranes into cells from beta cells
Insulin
The islets of the pancreas produce hormones (2)
-insulin
-glucagon
Helps establish the body’s wake and sleep
cycles
melatonin
allows glucose to enter the blood from alpha cells
Glucagon
maintain blood sugar homeostasis (2)
insulin
glucagon
Matures some types of white blood cells
thymosin
Found on the third ventricle of the brain
pineal gland
Secretes melatonin
pineal gland
May have other as yet unsubstantiated
functions
melatonin
thymus is largest in (2)
infants and children
Located posterior to the sternum
thymus
Important in developing the immune system
thymus
Produces thymosin
thymus
Hormones of the Ovaries (2)
Progesterone
Estrogens
Estrogens
Produced by
Graafian follicles or the placenta
Stimulates the development of secondary
female characteristics
Matures female reproductive organs
Helps prepare the uterus to receive a fertilized egg
Helps maintain pregnancy
Prepares the breasts to produce milk
estrogen
Acts with estrogen to bring about the
menstrual cycle
Progesterone
Progesterone
Produced by the
corpus luteum
Helps in the implantation of an embryo in
the uterus
Progesterone
__of testes are hormone producing
Interstitial cells
Hormones of the Testes Produce several
androgens
Testosterone is the most important
androgen
testosterone
Responsible for adult male secondary sex
characteristics
Promotes growth and maturation of male
reproductive system
Required for sperm cell production
Testosterone
Other Hormone Producing Tissues
and Organs (5)
Parts of the small intestine
Parts of the stomach
Kidneys
Heart
Many other areas have scattered
endocrine cells
Produces hormones that maintain the
pregnancy
Placenta
Most endocrine organs operate smoothly
until
old age
Some hormones play a part in the
delivery of the baby
Placenta
Placenta produces ___in addition to estrogen,
progesterone, and other hormones
HCG
is brought about by lack of
efficiency of the ovaries
Menopause
Problems associated with___
are common
reduced estrogen
__production declines with age
Growth hormone