Endo/Repro Flashcards
A middle-aged women with heavy menstrual bleeding, dysmenorrhea, and a uniformly enlarged uterus on PE most likey has what?
Adenomyosis: endometrial glandular tissue within myometrium
A bicornuate uterus is due to failure of what?
Incomplete lateral fusion of the paramesonephric ducts
What are the levels of LH, FSH, testosterone, and sperm like in pt with Klinefelter syndrome?
- High FSH and LH
- Low testosterone
- Absent sperm count
What does FSH and LH cause the release of in a male?
- FSH stimulates the release of inhibin B and androgen-binding protein from Sertoli cells in the seminiferous tubules
- LH stimulates the release of testosterone from the Leydig cells in the interstitium of the testicles
Describe how LH and FSH act on the ovarian follicle to produce androgens and estrogen; which cells are involved?
- LH stimulates production of androgens in the theca interna cells
- Released to granulosa cells, which contains aromatase for conversion of androgens –> estradiol under the influence of FSH
Leydig cells of the male testes are analogous in location and function to which cells of the ovarian follicle?
Theca interna cells
What is the most common congenital cardiac malformation seen with Turner Syndrome and what type of murmur does it produce?
- Bicuspid aortic valve
- Early systolic, high-frequency click heard over right 2nd ICS
High serum levels of what can confirm the diagnosis of 21-hydroxylase deficiency?
17-hydroxyprogesterone
Patient presenting with hyperglycemia (often newly diagnosed DM) and necrolytic migratory erythema affecting the groin, face, and extremities most likely has what?
Glucagonoma = 4 D’s (Diabetes, Depression, DVT’s, Dermatitis)
Which 2 conditions can arise in boys due to incomplete obliteration of the processus vaginalis?
- Hydrocele
- Indirect inguinal hernia
