EMT Pharmacology - Aspirin

Question 1

Pharmacology and presentation of Aspirin?

Answer 1

Comes in 300mg tablets.
An anti-platelet aggregator with analgesic, antipyretic and anti-inflammatory effects.
Inhibits cyclooxygenase reducing the formation of prostaglandins and thromboxane.

Question 2

Indicators of Aspirin?

Answer 2

• Myocardial Ischemia (MI)

Question 3

Cautions of Aspirin?

Answer 3

• Known bleeding disorder
• Clinically Significant bleeding
• Known worsening of bronchospasm from a NSAID

Question 4

Side Effects of Aspirin?

Answer 4

• Increased Bleeding

- Long term administration can lead to: indigestion, GI ulceration and GI bleeding

Question 5

Dosing Regimes of Aspirin?

Answer 5

300mg Orally

Question 6

Contraindications of Aspirin

Answer 6

• Hypersensitivity

- 3rd trimester of pregnancy

Question 7

Onset and duration of Aspirin?

Answer 7

Onset
‐ 30 to 60 mins

Duration
- 3 to 5 days as platelet life is 7 to 10 days