Embryology of the Heart Flashcards
Heart begins to beat around ______ days
22-23
Angioblastic cords form in week ___ in the cardiogenic area, which is at the ________ end of the embryo
3; cranial
Angioblastic cords canalize to _____________
Which fold to _____________
2 endocardial tubes
1 heart tube
5 dilations that appear at 22 days (caudal to cranial)
Sinus venosus Atrium Ventricle Bulbus cordis Truncus arteriosus
Faster growth of ________ & __________ leads to folding of the heart tube/heart
ventricles and bulbus cordis
Bend at junction of bulbus cordis and primitive ventricle
Bulboventricular loop
Blood flow through primitive heart BEFORE partitioning
sinus venosus -> primordial atrium -> atrioventricular canal -> primordial ventricle -> bulbus cordis -> truncus arteriosus -> aortic sac -> aortic arches
Sinus venosus remains as
coronary sinus & smooth inflow of RA
Primordial atrium remains as
Left auricle and rough part of RA
bulbus cordis remains as
conus arteriosus (RV) and aortic vestibule (LV)
Truncus arteriosus remains as
aorta and pulmonary trunk
first hole between R and L atrium
foramen primum
second hole between R and L atrium
foramen secundum
In utero, blood is allowed to be shunted from R to L. This happens through the _________
foramen ovale
After birth, typically with the first breath, the ____________ gets smashed up against the septum secundum, forming the ___________
Septum primum
Fossa ovalis
Remnants of the primitive atrium remain as the _______ _______
pectinate muscle
Remnants of the right sinus venosus remain as the ________ _________
sinus venarum
Pectinate muscle and Sinus venarum meet to form the _______ ___________
Crista terminalis
Remnants of the left sinus venosus remain as the _________ _________
coronary sinus
Most of left atrium in adult is formed by the _______ ________. The _____ _________ is the only remnant of the primitive atrium
pulmonary veins; left auricle
The membranous portion of the interventricular septum is formed by (2)
right endocardial cushion
aorticopulmonary septum
Bulbar ridges and Truncal ridges fuse to form the _________ __________
aorticopulmonary septum
Develop as swellings of endocardial cushions surrounding the AV canals
Atrioventricular valves
Develop from three swellings of subendocardial tissue at the junction between the bulbus cordis and truncus arteriosus
Semilunar valves
Formation of the outflow tracts occurs during week __ and involves formation of the _______ ________ which undergoes 180 degree spiraling
5; aorticopulmonary septum
Umbilical vein remains as
Round ligament of liver
Ductus venosus remains as
ligamentum venosum
foramen ovale remains as
fossa ovalis
ductus arteriosus remains as
ligamentum arteriosum
umbilical arteries remain as
medial umbilical ligaments
Four anomalies that make Tetralogy of Fallot
Pulmonary stenosis
Ventricular Septal Defect
Overriding/transposed aorta (over VSD)
Right ventricular hypertrophy