Embryology Flashcards
Cloaca
terminal portion of the hindgut, an endoderm lines cavity that is in direct contact with surface ectoderm. divides into two canals: one for solid and one for liquid waste
formation of greater omentum
dorsal mesogastrium buldge down over colon and SI to form a double layer sac greater omentum is the fusion between the two sheet.
what are the linings of the lungs?
endoderm lined splanchinic lateral plate mesoderm on outside
umbilical or vitelline fistula
vitelline duct remains patent over its entire length, connects umbilicus to intestinal tract. fecal discharge at umbilicus
Fixation of midgut
As intestines sit in final positions, mesenteries press against back wall of abdominal cavity. Ascending colon, duodenum become retroperitoneal The rest of the midgut (jejunum and ileum, cecum, appendix) are interperitoneal
Mesenteric changes of midgut
Descending and ascending get into position, they press against peritonum and become retroperitoneal. appendix, cecum and sigmoid are intermesternic.
Formation of perineal body
At week, fusion of urorectal spetum with cloacal membrane to divide into anal membrane and urogential membrane.
testicular migration
develop in lumbar region on dorsal abdominal wall as pelvis enlarges and trunk enlarges, gubernaculum does not grow and testes descend through inguinal canal during week 28 and takes 2-3 days move beneath peritoneum and behind processus vaginalis
what does the umbilical vein form?
Round ligament
Mesonephric duct
what drains urine in the mesonphric state. participate in the formation of the male genetical system by forming the ductus deferens and epididymis.
Mesentary proper
grows into jejunal and ileum SM a midgut region
what does foramen ovale form?
fossa ovalis
primary intestinal loop
forms during midgut physiological herniation. Part of the intestines that projects into the umbilical cord Upper arm is small intestines lower arm is terminal ileum, cecum, appendix and asecneding and part of transverse colon
anterior urorectal sinus
forms the primitive urogenital singus
Gonad development stepwise
1) primordial germ cells migrate to site of future gonadal ridge from near allontis to lumbar region 2) PGC induces thickening of gonadal ridge 3) week 6: PGC invade genital ridge and becomes enveloped by sex cords. 4) through reciprocal induction of PGC and cords, the gonad begins to develop.
pseudoglandular
first stage developing tissues resemble glands, but no gas exchange
Development of stomach
Due to differing growth rate foregut caudal to diaphragm grows faster and causes stomach to rotate right and caudal end to swing cranially thus what was left is anterior, and what is anterior is the lesser curvature
Cloacal membrane
composed of endoderm of the cloaca and ectoderm of anal pit.
Renal agenesis
failure to form kidneys because there was never a pronephric kidney. could be one side or both sides (both sides is not conducive to life)
what layer in the urinary system derived from
intermediate mesoderm - plate lying between paraxial mesoderm and lateral plate mesoderm and the cloaca`
Dorsal mesoduodenum
grows into duodenum CT
Cardiac looping
Cardiac loop bends at heart lengthens cranial goes ventrally, caudally to the right caudal, goes dorsal cranially and to the left Begins day 23 ends day 28
mesentary
double layers of peritoneum that enclose an organ or connect to body wall derived from splanchnic lateral plate mesoderm both dorsal and ventral mesentary
Dorsal mesocolon
grows into colon IM a Hindgut region
pronephric duct
formed during pronephro stage formed by union of mephrotomal vesicles that progress toward cloaca. The pronephros are though to induce mesonephric duct formation
formation of pancreatic duct
merging of vetnral and dorsal pancreatic buds. incomplete fusion can lead to accessory ducts
Formation of sex cords
in week six, primodridal germ cells invade genital ridge and become incorporated into sex cords. These proliferate and grow from coelmic epithilium into underlying mesenchyme. sex cords become the seminiferous tubules in males and medullary cords in females
Urorectal septum
ridge of mesenchye between the allontiois and hindgut. As is grows caudally to cloacal membrane, divides cloaca into anterior and posterior part.
Ductus venosus
To avoid umbilical blood through liver sinusoids bypasses heptaic portal from umbilical vein to IVC
Hepatic diverticulum
connects proximal 1/3 of duodenum with the stomach grows into ventral mesogastrium gives rise to gall bladder and bile ducts
what does ventral mesentary form?
lesser omentum falciform ligament
splanchinic mesoderm lining
forms smooth muscles, connective tissues and mesentary
parietal mesothilium
parietal peritoneal lining, on anterior body wall
Cranial folding for the heart development
Folding brings right and left endocardiotubes together Day 18-22
Dorsal mesogatrium
Dorsal mesentary that gives rise to the greater omentum Branches of Celiac trunk
Meckels diverticulum
condition where connection to yolk sack via vitellie duct persists for longer than usual and a remnant of the vitelline duct remains. Causes vitelline cysts (enteroceystoma) that contain gastric of pancreatic mucosa leads to bleeding and perforation
Basic development of urinary system
three kidney system; metanephros is preceded by 2 transitionary kidneys 1) pronephros 2) mesonephros 3) metanephros
allantois
connection between urinary bladder and amniotic space becomes a fibrous cord after birth called the urachus.
gubernaculum
a ligamentthat descends on each side of the lower poles of the testis/ovaries and passes obliquely down abdominal wall and attaches to labioscrotal swellings
Endoderm lining
forms lining of glands and gut tubes
terminal sac
third stage of lung development increased number of terminla sac, and alveoli can perform gas exchange
Reduction of midgut hernia
Intestines return to abdomen week 10 Jejunum returns first and settling behind SMa. The rest undergoes at 180 counterclockwise rotation to place cecum and appendix near right lobe of liver where they descend into right fossa. Total rotation is 270° it returns due to decrease in relative size of liver and mesophrenic kidneys, as well as abdominal enlargement and expansion
Pancreas development
ventral pancreatic bud in the ventral mesogastrium dorsal pancreatic bud int he dorsal mesogastrium as the dorsal bud grows, it rotates left and it retroperitoneal. Ventral bud (uncinate process) grows and rotates left 270° to fuse with dorsal bud
cord cells of ovary
forms follicular cells that surround oocyte
uteric bud
an outgrow of the mesonephric duct also called metanephric diverticulum branches to produce factors that produce the metanephric blastoma gives rise to ureter, renal plevis, renal calyces, collecting tubes and ducts.
Pronephros
primitive and non-functional kidey Begins at beginning of 4th week and ends at end of 4th week At level c5-c7
primordial germ cells
from indifferent genital stage originate in epiblast and migrate to wall of yolk sac near origin of allantois.
mesencyme cells of ovary from
stromal cells - supportive cells of ovary
Development of testis
due to XY composition 1) Y chromosome releases a SRY (transduction factor on Y chromosome) 2) that signals the release of the TDF (testis determination factor) 3) directly causes cord cells to transform into sertoli cells that support spermatogenesis and make up furture efferent ductules. 4) the Sertoli cells release a mullarian inhibitory factor that triggers the aponeurosis of the mullarian ducts. 5) TDF also indirectly gives rise of leydig cells from mesencyme. 6) leydig cells release testosterone to promoe external genetalia and male genital ducts
rotation in umbilical cord of proximal intestinal loop
fortates 90° around axis of superior mestenteric artery so that the proximal limb is on the right and distal limb is on the left. This is when branching of the SMa occurs.
posterior urorectal sinus
forms the anocrectal canal
ventral mesentary
exists only in foregut (esophagus, stomach and upper duo) due to extension of septum transversum associated with liver, bilary tree, ventral pancreas grow into it
Compartmentalization of intraembyonic coelom
Pleuropericarinal exens anteriorly to close the pericardioperitoneal canal. This is moving towards the septum transversum.