EM/Toxicology Flashcards
Treatment of subdural and epidural hematoma
subdural = crescent epidural = lens both: 1. intubation + HYPERVENTILATION 2. Mannitol 3. Mannitol
When can you do a percordial thump?
- <10 min aka you saw them drop
- no pulse
- no AED around
what is the CHADS2 score?
criteria to give anticoags for A-fib
CHF, HTN, Age>75, DM, Stroke/TIA , 2+ gets anticoag w/goal INR 2-3
In the case of toxicology when do you do “gastric emptying/gastric lavage”?
only if within 1hr after overdose & OD was not with acids or bases
In the case of toxicology when do you do “whole bowel irrigation”?
iron ingestion, lithium, drug filled packets(butt cocaine)
In the case of toxicology when do you do give “naloxone, thiamine & dextrose”?
anytime there is acute mental status changes of unclear etiology = naloxone wont hurt anyone so give this first
In the case of toxicology when do you do give “charcoal”?
most cases. this wont hurt anyone
1 cause of OD in the USA? whats #2?
Acetaminophen, #2 is ASA
SX of Acetaminophen tox?
first 24hrs = nausea and vomiting
>24 hrs(48-72) = hepatic failure
Antidote for Acetaminophen
when do you give this?
N-Acetylcysteine = give to ANY patient with acetaminophen OD before you check levels; only give if within 24 h
Toxic acetaminophhen levels? deadly?
10g = toxic; 15g = deadly
Antidote for ASA
Bicarbonate to alkalinize the urine
Antidote for Benzodiazepines
when do you give this?
Flumazenil = only give if you know for sure the person isnt a chronic user. if you give to a chornic user can get a seizure = better to just let them ride it out. benzos wont kill you
Antidote for Carbon monoxide poisoning
100% O2, Hyperbaric o2 if severe
Antidote for digoxin
digoxin-binding antibodies
Antidote for Ethylene glycol
fomepizole or ethanol; same as methanol
Antidote for methanol
fomepizole or ethanol; same as ethylene glycol
Antidote for Methemoglobinemia
methylene blue
Antidote for Neuroleptic Malignant Syndrome
bromocriptine, dantrolene
Antidote for Opiates
naloxone
SX of ASA poisoning? what labs would you see?
- this is a brain stimulant and a toxin to the lungs =
- metabolic acidosis = lactic acidosis from hypoxic metabolism
- respiratory alkalosis = hyperventilation
- renal insufficiency = anion gap
- elevated prothombin time
- CNS: confusion
- Fever
- Tinnitus***
normal pH, low PCO2(rep. alk), low HCO3(met acid)
can you overdose on benzos and dies? why is this important when considering antidote?
nope! not fatal by itself so dnt give flumazenil for OD unless you kn`ow the person isnt a chronic user. if they are a chronic user it can precipitate seizures
MCC of death in fires?
CO poisoning
sx of CO poisoning?
**looks like anemia w/cherry red blood = blood unable to release O2 into tissue
- SOB, lightheadedness, HA, disorientation, metabolic acidosis(tissue hypoxia), fatigue
tx: 100% O2
Digoxin Tox sx? tx?
yellow “halos” around objects, arrhythmia w/downsloping of ST segments, Encephalopathy, Hyperkalemia
tx: dig. antibodies
Whats up with potassium and digoxin
K & Dig compete for the same spot on NaK. so Hypokalemia can trigger dig toxicity(recent use of lasix) but dig tox causes hyperkalemia
Sx of Ethylene Glycol/Antifreeze poisoning
renal insufficiency = envelope shaped oxalate crystals, hypocalcemia, kidney stones, hypocalcemia, kidney stones
sx of Methanol poisoning
- wood alcohol, cleaning solutions, pain thinner
sx: visual disturbances(ocular toxic = retinal inflammation), retinal hyperemia
sx of Methemoglobinemia
- Hg locked into the oxidized state = cant pick up oxygen
- like anemia but w/o oxygen
- cyanosis, SOB, Dizziness, Confusion, HA, Seizures
What should you look for in the history for methemoglobinemia?
hx of nitrate use, anethetics, dapson, or other oxidants or drugs that end with -caine
tx of methemoglobinemia
100% O2 & Methylene blue
Sx of Organophosphate/Nerve Gas
- blocks AChE so will have sx of increased ACh
- salivation, lacrimation, urination, diarrhea, wheezing from bronchospasm, constricted pupils
tx of organophosphate/nerve gas
- atropine
- pralidoxime
- remove clothes & wash the rest of hte patient
sx of TCA overdose
Coma, Cardiac(arrhythmias = wide QRS), Convulsions(seizures)
+ anticholinergic sx = dilated pupils, dry mouth, constipation, urinary retention
tx of TCA overdose
NaHCO3 to protect the heart & give IVF to flush out
Hypothermia sx? tx?
cardiac shit = this is what kills!
EKG = J-waves of Osborn