Electron Transport Chain

Question 1

Final common pathway by which electrons from various metabolic substrates are passed and the gradient used to synthesize ATP

Answer 1

ETC

Question 2

ETC is found in which part of the mitochondrial membrane

Answer 2

Inner Membrane

Question 3

Which components of the ETC are mobile

Answer 3

Q

Cytochrome C

Question 4

Complex in ETC where molecular O2 is reduced to water

Answer 4

Complex 4
or
Cytochrome C Oxidase

Question 5

Theory where the proton motive force drives the synthesis of ATP

Answer 5

Chemi-osmotic theory

Question 6

Where the ETC complexes act as H pumps

Answer 6

Complex
1
3
4

Question 7

What are the complexes of the ETC

Answer 7

1 NADPH-Q-Oxido-reductase
2 Succinate-Q-Reductase,
3 Q-Cytochrome C,
4 Cytochrome C Oxidase

Question 8

Affect on ETC:

Malonate

Answer 8

Complex 2 inhibitor

Question 9

Affect on ETC:

Carboxin

Answer 9

Complex 2 inhibitor

Question 10

Affect on ETC:

Thermogenin

Answer 10

Uncoupler

Question 11

Affect on ETC:

Anti-mycin A

Answer 11

Complex 3 inhibitor

Question 12

Affect on ETC:

Oligomycin

Answer 12

ATP synthase inhibitor

Question 13

Affect on ETC:

Amobarbital

Answer 13

Complex 1 inhibitor

Question 14

Affect on ETC:

Rotenone

Answer 14

Complex 1 inhibitor

Question 15

Affect on ETC:

Cyanide

Answer 15

Complex 4 inhibitor

Question 16

Affect on ETC:

Carbon monoxide

Answer 16

Complex 4 inhibitor

Question 17

Affect on ETC:

Azide

Answer 17

Complex 4 inhibitor

Question 18

Affect on ETC:

Atractyloside

Answer 18

ADP ATP transport inhibitor

Inhibitor of Oxidtive phosphorylation

Question 19

Affect on ETC:

2,4 dinitrophenol

Answer 19

Uncoupler

Question 20

MELAS

Answer 20

Myopathy
Encephalopathy
Lactic acidosis
Stroke-LIKE episodes

Question 21

Final electron acceptor of ETC

Answer 21

Oxygen