ELECTROLYTES PART 1 (ANIONS) Flashcards
What are the ANIONS
- Cl-
- HCO3-
- PO42-
- Major anion in the ECF.
Chloride (Cl-)
- Counter ion of Na- always accompany Na to maintain electric neutrality.
Chloride (Cl-)
- Lost or excreted in sweat.
- Only anion that enzyme activator-activates amylase
- Regulated by aldosterone.
Chloride (Cl-)
Chloride (Cl-) FUNCTIONS:
- Maintain water balance and osmotic pressure.
- Acid-base balance
- Maintenance of electrolyte balance/electroneutrality (Chloride shift)-exchange with HCO3 across the RBC membrane.
- Hydration.
- Causes: DKA, aldosterone deficiency, vomiting, high serum bicarbonate. Metabolic alkalosis, diuretics.
Hypoclorenemia
- Causes: metabolic acidosis, renal tubular acidosis, excess loss of bicarbonate, cystic fibrosis, CHF, hyperthyroidism, severe diarrhea
Hyperchlorenemia
Intracellular anion.
absorption in small intestines.
Phosphate (PO4)
most are in the form of inorganic phosphate (serum)
Phosphate (PO4)
In complex with magnesium and calcium
Phosphate (PO4)
Phosphate are __% of plasma inorganic phosphorus are organic and ___% are inorganic.
70%
30%
- Majority of inorganic phosphate is excreted in _____ and ____ favors urinary loss of phosphorus
urine
PTH
Causes:
a. hyperparathyroidism
b. rickets
c. osteomalacia
d. Fanconi’s syndrome
Hypophospathemia
Causes:
a. hypoparathyroidism
b. increase Vit D
c. hypersecretion of growth hormone
d. uremia
e. glomerulonephritis
Hyperphosphatemia
- 2nd most abundant anion in ECF
Bicarbonate (HCO3- )
Bicarbonate (HCO3- ) Functions:
- Major buffering system of the blood.
- Exchange with Cl across the RBC to maintain ionic charge neutrality within the cell (chloride shift).
Bicarbonate (HCO3- ) Decrease in:
- Metabolic acidosis
- HCO3- combines with hydrogen ion (H+ ) to produce CO2 which is exhaled by the lungs.