Ecephalitis Flashcards
Encephalitis
Acute inflammatory disease fo brain tissue caused by viral infection or hypersensitivity initiated by virus
Primarily in grey matter of CNS
West Nile or herpes simplex cause
Either encephalitis or meiningitis
WNV responsible for cases of
Meningitis
Encephalitis
Poliomyelitis
Risk factors
Dependent on mostquitos
Mid to late summer
Eastern from is less common, more deadly
Conditions that have potential to increase complications
DM HTN COPD Demential CAD ETOH CA Immunosuppressive
West Nile
Replicate dendritic cells, spread to lymph nodes, blood stream, invade NS
Perivasuclar lymphoplasmacytic inflitatiration, necrosis, neuronal loss
WNV structure preference
Thalamus
BS
Cerebella purkinje cells
WNV symptoms
Flu like
Fever HA Malaise Myalgia Fatigue Skin rash Lymphadenopathy Vomiting Diarrhea
WNV presentation
Kernite and budzunski may be positive
May present as acute flaccid paralysis
Herpes simplex
Common in neonates and infants
Acquired - birth canal
May be repeated seizure activity
Epstein-Barr virus
Acute encephalitis occurs during course of systemic infection
Creates CNS dysfunction
Encephalomyelitis
Result from viral infections:
MMR or varicella
Echephalitis S/S
Depend on etiologic agent
General: HA, nausea, vomiting, ALOC
Coma
Hemiparesis, aphasia, ataxia
Encephalitis DX
MRI - rebrand edema and vascular damage, WNV lesions sometimes seen
WNV lesions
White matter
Pons
Substantial Nigeria
Thalamus
