Cerebral Hemispheres And Vascular Supply Flashcards
% of problems in cranial cavity that are vascular
50
Loss of consciousness occurs when
The brain is deprived of oxygen for ~10 seconds, after ~3 minutes brain damage will result
After 10 minutes, brain death
No dominant hemisphere
(Right), association cortex (parietal lobe > frontal lobe) attention to contralateral
Circle of Willis
Anterior - internal carotid arteries
Posterior- vertebrobasilar
Circle of Willis
-and and posterior circulation joined by this circle
-provides opportunity for collateral blood flow
-major cerebral vessels arise from Circle of Willis
Main arteries supplying cerebral hemispheres
Anterior circulation-terminal branches of ICAs
Anterior cerebral arteries - jointed by anterior communicating artery
Middle cerebral arteries
Main arteries supplying cerebral hemisphere
Posterior circulation
Vertebral arteries-converge to form basilar
Posterior cerebral arteries - arise from top of basilar
Posterior communicating arteries - join ICAs and PCAs. Joins anterior circulation to posterior circulation
Three main cerebral arteries
ACA, MCA, PCA
Gives off numerous branches that travel over surface of brain and into sulci-supply superficial cortex and underlying white after
Gives off small branches that arise from initial segments of cerebral arteries at base of brain to supply deeper structures- BG, thalamus, internal capsule
Anterior cerebral artery
Supplies most of the anterior medial surface of the cortex from the frontal to anterior parietal lobes
Anterior portion of caudate nucleus
Putamen
Internal capsule
Middle cerebral artery
Most of lateral cortex
Enters Sylvian fissue to bifurcate into superior and inferior divisions
Most of caudate nucleus, putamen, globes pallidus, genu of internal capsule
Superior division of middle cerebral artery
Cortex about sylvian fissure (lateral frontal lobe and most of insula)
Inferior division of middle cerebral artery
Supplies cortex below sylvian fissue (lateral temporal lobe and portion of parietal lobe)
Posterior cerebral artery
Inferior and medial temporal lobes
Medial occipital cortex and most of medial parietal cortex
Thalamus and hippocampus
Lenticulostriate artiers
Small penetrating vessels at base of brain
Arise from initial portions of MCA before it enters sylvian fissure
Portions of basal ganglia and internal capsule
Anterior choroidal artery
Arise from ICA
Posterior limb of internal capsule
Portion of globes pallidus, putamen, lateral thalamus
Ischemia events are most common in
MCA
Ischemia in MCA- three divisions
- Superior division
- Inferior division
- Deep territory
Stem infarcts
Proximal MCA occlusion affecting superior, inferior and deep territory divisions
Left MCA superior division
- right face and arm weakness
- UMN type
- non fluent or brocas aphasia
Cortical-type sensory loss- problems with localization and/or higher order sensory functions -
Left MCA inferior division
- Fluent or wernicke’s aphasia
- right visual field deficit
- Right face and arm cortical type sensory loss
- mild right sided weakness may be present (edge of motor cortex)
Left MCA deep territory
- Right pure motor hemiparesis UMN-BG and left upper posterior internal capsule (descending CTS)
- Aphasia - axons to broca’s or wernicke’s
Left MCA stem
- Combo of deficits for MCA
- Right hemiplegia
- R hemiansesthesia- PSC, sensory association cortex and left upper posterior internal capsule
- R homonymous hemianopia
- Global aphasia - broca’s and wericke’s
- Left gaze preference - damage to left frontal eye fields and parietal cortical areas (normally drive eye movements toward opposite side)
Left ACA
- right leg weakness UMN and cortical type sensory loss
- Grasp reflex - presence of primitive reflexes (frontal release signs)
- frontal lobe behavioral abnormality
- Transcortical motor aphasia- normal comp and repetition is spared but impaired fluency (language areas in frontal lobe)
- large infarcts cause Right hemiplegia - ACA territory could extend to UE motor cortex (rare)
Right ACA
- left leg weakness UMN and cortical type sensory loss
- grasp reflex
- frontal lobe behavioral abnormalities
- Left hemineglect - right frontal lobe (r hemisphere is spatial awareness)
- larger infarcts may cause hemiplegia
Right MCA superior division
- left face and arm weakness UMN
- Left hemineglect (right hemisphere - spatial awareness)
- may have some left face/arm cortical type sensory loss
Right MCA inferior division
- Profound left hemineglect (r parietal - visual cortex and right hemisphere is spatial awareness
- left visual field and somatosensory deficits (hard to test)
- Motor reflect w/ decreased voluntary or spontaneous initiation on left side
- some mild left sided weakness
- often right gaze preference
Right MCA deep territory
- left pure motor hemiparesis of UMN
- large infarcts produce cortical deficits like left hemineglect
Right MCA stem
- left hemiplegia
- left hemianestesia
- left homonymous hemaniopia
- profound hemineglect
- right gaze preference
left PCA
- right homonymous hemianopia
- extension to selenium of corpus callosum—alexia without agraphia (reading impairment without writing impairment-prevents processing of written material due to damage of post CC and left PVC)
- larger infarcts to thalamus and internal capsule: aphasia, right hemisensory loss, right hemiparesis
Right PCA
- left homonymous hemianopia
- large including thalamus and internal capsule: left hemisensory loss and hemiparesis
Watershed infarcts
Regions b/n cerebral arteries are called watershed zones
Can occur where the cerebral vascular territories meet-where brain parenchyma is furthest from the arterial supply making it most vulnerable to reductions in perfusion
ACA-MCA zone
MCA-PCA zone
ACA-MCA watershed infarct
- sudden occasion of an ICA
- drop in BP in pt w/ carotid stenosis
Can produce proximal arm and leg weakness (homunculus regions would include proximal limbs and trunk)
MCA-PCA watershed infarcts
Problems w/ higher order visual processing
Interrupts pathway from PVC to visual association cortex
Bilateral watershed infarcts
Both ACA-MCA and MCA-PCA can occur w/ severe drops in systemic BP
Risk factors for ischemic event
Hypertension Diabetes Hypercholesterolemia Cigarette smoking Positive family hx Cardiac disease Prior history of stroke or other vascular disease