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Exam 1: DHHD 5001 > Early Tooth Development (Larsen 2) > Flashcards

Early Tooth Development (Larsen 2) Flashcards

1
Q

Two tissues required by odontogenesis

A
  • Oral ectoderm (epithelium)

- Ectomesenchyme (dental mesenchyme) (connective tissue)

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2
Q

Oral ectoderm

A

Oral epithelium that forms enamel organ

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3
Q

Ectomesenchyme (dental mesenchyme)

A
  • Connective tissue
  • Neural crest origin
  • Forms dentin and pulp of both crown and root
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4
Q

Life cycle of a tooth

A
  • Growth (Initiation, Proliferation, Morphodifferentiation, Histodifferentiation, Apposition [adjacent but different, like enamel and dentin])
  • Calcification/Mineralization
  • Eruption
  • Attrition
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5
Q

Initiation: ______ is the first sign of tooth development, is a horseshoe-shaped thickening of the oral epithelium, and develops around 6 weeks in utero.

A

Dental lamina

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6
Q

Initiation: The _____ is an epithelial thickening that forms along ten specific points called ______ on both the mandibular and maxillary arches.

A
  • Tooth bud

- Dental placode (becomes specific teeth)

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7
Q

Tooth bud stage: oral epithelium grows down into the _____.

A

Ectomesenchyme

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8
Q

Tooth bud stage: growth of oral epithelium becomes bulbous and resembles a ____.

A

Boot

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9
Q

Tooth bud stage: mitosis takes place on _____ and _____ causing a ______.

A
  • Superior surface
  • Distal tip
  • Concavity
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10
Q

Tooth bud stage: oral epithelium will form _____.

A

Enamel

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11
Q

Tooth bud stage: Ectomesenchyme in cavity will become ______.

A

Dental papilla

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12
Q

Steps from dental lamina to tooth bud

A
  • Dental lamina
  • Elongation
  • Tooth bud
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13
Q

In the cap stage, cells become ____ and ____ different.

A
  • Functionally

- Morphologically

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14
Q

Outer Layer of the Enamel Organin Cap Stage (Outer enamel epithelium)

A

Single layer of cuboidal epithelium along the convexity of the cap

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15
Q

Inner Layer of the Enamel Organ Cap Stage (Inner enamel epithelium)

A

Single layer of low columnar cells along the concavity of the cap

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16
Q

Middle Layer of the Enamel Organ Cap Stage (Stellate reticulum)

A

Stellate shaped cells separated by glycosaminoglycans

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17
Q

Dental Papilla in Cap Stage: _______ in the concavity underneath the ______.

A
  • Ectomesenchyme

- Inner enamel epithelium

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18
Q

Dental Papilla in Cap Stage: Forms the _____ and ____ of the crown

A
  • Dentin

- Pulp

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19
Q

Dental Sac or Follicle in Cap Stage: ______ surrounding the developing enamel organ and dental papilla

A

Ectomesenchyme

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20
Q

Dental Sac or Follicle in Cap Stage: Will form ______, ______, and ______.

A
  • Cementum
  • Periodontal ligament
  • Alveolar process
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21
Q

Cervical Loop in Cap Stage: ______ rim of the enamel organ formed by ______.

A
  • Outer

- Outer and inner enamel epithelium

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22
Q

Cervical Loop in Cap Stage: Is later involved in ______ formation.

A

Root

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23
Q

Cap Stage Summary: Proliferation of growth by mitosis of ______ cells resulting in _____ morphology.

A
  • Epithelial

- Concave

24
Q

Cap Stage Summary: Three layers in the enamel organ

A
  1. Outer enamel epithelium
  2. Inner enamel epithelium
  3. Stellate reticulum
25
Q

Cap Stage Summary: _______ at the outer rim of the enamel organ

A

Cervical loop

26
Q

Cap Stage Summary: Ectomesenchyme forms _______.

A

Dental papilla

27
Q

Cap Stage Summary: ______ surrounds enamel organ and dental papilla

A

Dental sac

28
Q

Shaping of the tooth such as incisor or molar

A

Morphodifferentiation

29
Q

Differentiation of ameloblasts from the inner enamel epithelium

A

Histodifferentiation

30
Q

Differentiation begins at the ______ and moves ______.

A
  • Cuspal tip

- Cervically

31
Q

Differentiation of odontoblasts from the dental papilla

A

Histodifferentiation

32
Q

Name and describe the inner layer of the bell stage enamel organ

A

Inner enamel epithelium - columnar cells that form ameloblasts

33
Q

The ______ is a cluster of non-dividing epithelial cells that orchestrates cuspal morphogenesis.

A

Enamel knot

34
Q

Name and describe the outer layer of the bell stage enamel organ

A

Outer enamel epithelium - Avascular (fed by blood vessels in follicle)

35
Q

Name the new layer of the bell stage enamel organ

A

Stratum intermedium

36
Q

The ______ is composed of two to three layers of cells on the surface of the inner enamel epithelium and is the nutritional layer needed for the formation of enamel.

A

Stratum intermedium

37
Q

Name and describe the middle layer of the bell stage enamel organ

A

Stellate reticulum - continued secretion of GAGs to allow growth of the crown

38
Q

Dental papilla in bell stage

A
  • Odontoblasts

- Dental Pulp

39
Q

Describe odontoblasts of dental papilla in bell stage

A

Terminally differentiated cell; cells next to the basement membrane start secreting the organic matrix of mantle dentin

40
Q

Describe the dental pulp of dental papilla in bell stage

A

The central portion of the connective tissue also contains the blood vessels and nerves

41
Q

The bell stage dental sac or follicle is composed of _______ of neural crest origin and forms ____, _____, and ____.

A

-Ectomesenchyme
-Periodontal ligament
-Cementum
Alveolar process

42
Q

The bell stage ______ is where the inner enamel epithelium and the outer enamel epithelium meet.

A

Cervical loop

43
Q

The _____ will be involved in the formation of the root after the crown has fully formed.

A

Cervical loop

44
Q

In the bell stage, the cells of the ______ continue to divide.

A

Cervical loop

45
Q

Crown Formation: the inner enamel epithelium is constrained between the ______ and _____.

A
  • Cervical loop

- Cusp tip

46
Q

Crown Formation: ______ forms as a result of cell proliferation

A

Cuspal outline

47
Q

Crown Formation: Future cusp is pushed up toward the _______.

A

Outer enamel epithelium

48
Q

Bell Stage Summary: Four layers of the enamel organ

A
  1. Outer enamel epithelium
  2. Inner enamel epithelium, ameloblasts
  3. Stellate reticulum
  4. Stratum intermedium (NEW)
49
Q

Bell Stage Summary: Two layers of dental pulp

A
  1. Dental papilla

2. Odontoblasts (NEW)

50
Q

Bell Stage Summary: Cell surrounding enamel organ and pulp

A

Dental sac or dental follicle

51
Q

______ is a thickening of oral epithelium lateral to dental lamina in which cells grow downward into the connective tissue and degenerate forming a cavity.

A

Vestibular lamina

52
Q

______ is an extension of the dental lamina lingual to the primary tooth and forms ___ of the permanent teeth.

A
  • Successional lamina

- 20

53
Q

Parent dental lamina

A

Remains of the original lamina

54
Q

Lateral lamina

A

Connects developing primary tooth to parent lamina

55
Q

Permanent molars are derived directly from the distal portion of the _______ without a primary tooth precursor.

A

Dental lamina

56
Q

Successional lamina is _____ to primary tooth.

A

Lingual

57
Q

Degeneration of the Parent Dental Lamina: During the bell stage the enamel organ loses contact with the ________ when the parent (general) lamina degenerates, which may leave islands of epithelial cells in the connective tissue.

A

Oral epithelium

Exam 1: DHHD 5001 (14 decks)

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