E1 catalyzes rxns 1 and 2 with a handoff to E2

Question 1

Ylid

Answer 1

Ylid is a dipolar ion. We are interested in the minus, which has occurred becayse there is a Hydrogen that has been lost (gives - charge, carbanion then becomes nucleophile)

Ylid is a great e- sink due to resonance.

Question 1

What is happening at the end of E1 catalyzed rxn?

Answer 1

In this reaction, at the end of it , we are handing off to E2, which is involved at the end of the rxn.

Question 2

Nestled CC

Answer 2

There is a second CC that starts and finishes before you finish the original CC.

Question 3

TAZ

Answer 3

becomes nucleophilic carbanion which does nuc attack.

Question 4

Hidden redox rxn

Answer 4

E1 is the dehydrogenase… There is an ox coupled with a reduction… Sulfurs such as formation of disulfide can be a redox change. (taking S-H to make S-S)

The disulfide is getting reduced to an SH?