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C.M. P
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Decks in this class (31)
Reciprocal Control & substrate cycles
What is reciprocal control,
When two,
Each substrate cycle has what
5
cards
more about HK-IV (GK)
Hk iv must do what,
How is liver glucose usually stor...,
How is hk iv regulated
19
cards
Oscillations and diversions
Why do concentrations of metaboli...,
Glycolysis and gng regulation is,
Muscular exertion and feeding fas...
3
cards
PFK-1, FBPase-1, F26P and 2nd substrate cycle
F26p is a key regulator in,
If glucagon high,
If insulin high
3
cards
PFK-2/FBPase-2 "flux controller enzyme"
F26p,
Flux controller activity,
Allosteric regulation of flux con...
3
cards
F26P and liver glucose blood reg
Dephosphoenzyme,
Phosphoenzyme,
Low blood sugar
6
cards
Examples of F26P and flux in other tissues
Why do tissues control systems di...,
Skeletal muscle,
Heart
3
cards
Into/out of the TCA
Other ways to get energy other th...,
If pyruvate is converted to lactate,
What to do with tca
3
cards
TCA's chemical strategy
Tca supplies reactants for biosyn...,
Coa,
Three groups of high energy compo...
5
cards
Mammalian PDHC
Where is pdhc occurring,
What are the three enzymes in the...,
Complex structure
13
cards
Important chemistry for two PDH cofactors
Thioesters,
Why high energy,
Flavin cofactors
3
cards
PDHC rxn outline
Mammals have many lipolysine lipo...,
2
cards
E1 catalyzes rxns 1 and 2 with a handoff to E2
Ylid,
What is happening at the end of e...,
Nestled cc
6
cards
E1's Proton Wire
Proton in step 2 of rxn 1 catalyz...,
Proton wire,
Each tpp is bound where
6
cards
E2 Catalyzes Rxn 3
E2 lipoyl arm,
Peripheral subunit binding domain,
How many lipoyl domains do we have
8
cards
E3 catalyzes rxns 4 and 5
E3 has what,
Oxidized e3,
What is a disulfide interchange
12
cards
PDHC regulation by its PRODUCTS
Regulation of pdhc is important why,
Nadh and acetyl coa compete with ...,
Ratios
12
cards
PDHC physiology in oxidative tissues
Oxidative tissues,
Pdh,
When liver has greattest glycolyt...
7
cards
TCA's overall chemical strat
Tca,
Oxidation of c involves,
Net rxn tca
6
cards
Citrate Synthase, CS
Cs mech,
Structure of cs,
What type of rxn occurs here
10
cards
aconitase
Aconitase,
Citrate,
4 fe 4s
13
cards
Isocitrate Dehydrogenase (IDH)
Structure of idh,
Importance of idh,
Stereospecificity
7
cards
a-KGDH complex
Function of a kgdh,
3 differences between a kgdh and ...,
Similarities to pdhc
4
cards
Succinyl-coA synthetaste (SCS)
First step rxn type,
Second step rxn type,
Third step rxn type
11
cards
succinate dehydrogenase (SDH)
In this rxn,
When would use nad,
Fad
7
cards
Fumarase and Malate DH (MDH)
Malate dh,
Fumarase,
Free energy mdh
3
cards
TCA's reg & connection to PDHC reg
Etc ocphos,
Tca makes,
Cs
8
cards
glycogen metabolism
In,
G6p,
Muscles contain how much glycogen
8
cards
glycogen metabolism P2.
Whyy have glycogen store when fat...,
Glycogen particle,
Regula
9
cards
Glycogen phosphorylase (GP)
Structure,
N terminal crevice,
Where is actve site
10
cards
mechanism of glycogen phosphorylase
Gabc,
Blocked face sn1,
C1 s glycosidic bond
7
cards
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biochem exam 4
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