E. coli

Question 1

ETEC (enterotoxigenic E. coli) exotoxin

Answer 1

one exotoxin is called LT stands for heat labile exotoxin. has homolOgy with cholera exotoxin. AB5 exotoxin uses same receptor and has same fn

Question 2

ETEC (enterotoxogenic E. coli) exotoxin

Answer 2

one exotoxin is called LT stands for heat labile exotoxin. has homolOgy with cholera exotoxin. AB5 exotoxin uses same receptor and has same fn

Question 3

ETEC (enterotoxogenic E. coli) exotoxin

Answer 3

one exotoxin is called LT stands for heat labile exotoxin. has homolgy with cholera exotoxin. AB5 exotoxin

Question 4

EHEC enterohemorrhagic E coli 1st virulence factor

Answer 4

senses furose in environment and produces 2 virulence factor. 1st is adhesin called intamin, after ingestion E. coli uses pili to bind weakly to intestinal epithelium. PAI that ecodes intamin, a T3SS and intamin receptor called Tir

Question 5

what does EHEC using T3SS for

Answer 5

uses T3SS to intorduce tir into host cytoplasm. host will phosphrylate tir and insert it into PM. E.coli then used intamin to bind to tir for stronger bonding

Question 6

EHEC 2nd virulence factor

Answer 6

stx (shiga exotoxin) is similar to one by Shigella. stx genes are phage encoded, a AB5 exotoxin. B subunit binds to receptor on vascular intestinal endothelium cells, transported to golgi and then adheres to RER. A subunit transported from RER to cytoplasm.