3) invasion of mucous membrane (not all bacteria do this)

Question 1

directed uptake

Answer 1

some can attach and direct epithelial cells to term them up by endocytosis e.g. Salmonella (more later)

Question 2

exploitation of antigen sampling process e.g.

Answer 2

Shigella gets taken up by M cells in intestine and delivered to macrophage by transcytosis. macrophage takes up the bacteria by endocytosis

Question 3

when Shigella is in the macrophage what happens

Answer 3

induces apoptosis of macrophage and escapes. then attaches to specific receptor at base of intestinal cell and directed endocytosis. grows and can spread to adjacent cells

Question 4

bacteria that avoid complement are called

Answer 4

serum resistant

Question 5

serum resistant bacteria bind

Answer 5

complement component factor H. Factor H inactivates any C3b that bind to bacterial cell which inhibits the complement system