C) Antibiotics that target protein synthesis Flashcards

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1
Q

tetracycline is isolated from

A

Streptomyces

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2
Q

structure of tetracycline

A

4 linked ring

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3
Q

fn of tetracycline

A

binds to 30S ribosomal subunit and blocks charged tRNA from entering A site, stopping elongation

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4
Q

problems of tetracycline

A

tendency to kill normal flora, can result in overgrowth of opportunistic pathogen

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5
Q

tetracycline resistance

A

a plasmid encoded efflux system

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