DSA Environmental Lung Injury Flashcards
PFT of pneumoconioses would show which pattern?
restrictive
how many years of exposure before pneumoconioses form?
about 20 years
4 pathogens that cause pneumoconioses
- berrilym
- coal
- asbestos
- silica
asbestosis may cause which condition?
mesothelioma
10% develop this
radiographic findings of asbestosis
pleural changes in periphery
smoking + asbestosis exposure increases risk by
75 x
laboratory finding for asbestosis
ferruginous bodies
(via lung biopsy)
tx for asbestosis
supportive: vax
transplant
most common pneumoconiosis
silicosis
MC infections associated w/silicosis
mycobacterium
test yearlyWhy are patiens with silicosis more prone to mycobacterial infection?
silica is cytotoxic to alveolar MF
test yearly
Radiographic findings: silicosis
“egg-shell calcifications”
How is berylliosis diagnosed?
blood berylium lymphocyte proliferation test (BeLPT)
CXR findings: berylliosis (2)
- diffuse intersttitial infiltrates
- “light bulb”-appearing granulomas
coal miners lung
“black lung”
nodular opacities