Drugs used to treat hypertension Flashcards
How do ACE inhibitors work?
They block the conversion of angiotensin 1 to angiotension 2 by stopping the ACE in the ungs which stops the renin-agiotnsin-aldosterone system and preventing vasoconstriction.
How do angiotensin receptor blockers work?
They bind to angiotensin receptors to prevent vasoconstriction and the release of aldosterone
How do calcium channel antagnist work?
They prevent the moveent of calcium into the cardiac and smooth muscle cells and interfere with the muscles ability to contract.
How do beta-blockers work?
They decrease the releas of renin to prevent vasoconstriction and cardiac contration and increase blood flow to the kidneys
How do apha-blockers work?
They inhibit post-synaptic alpha-adrenergic receptors which block the action of NaCI and adrenaline. This decreases sympathetic tone and causes vasodilation
How do thiazide-like diuretics work?
They increase the excretion of sodium and water from the kidneys which affects blood volume and lowers blood pressure
How do vasodilators work?
These are for emergenices and cause direct vasodilation
What are example of ACE inhibitors?
- Captpril
- Enalapril
- Moexipril
- Ramipril
What are example of angiotensin receptor blockers?
- Cardeartan
- Eprosartan
- Irbesartan
- Olmesartan
What are examples of calcium channel blockers?
- Amlodipine
- Felodipine
- Isradipine
- Nicardipine
- Verapamil
What are examples of Beta-blockers?
- Atenolol
- Metaprolol
- Propanolol
- Sotalol
What are examples of Alpha-blockers?
- Prozosin
- Terazosin
- Doxazosin
What are examples of thiazide-like diuretics?
Bendroflumethiazide
What are examples of vasodilators?
- Diazoxide
- Hydrazine
What are the side effects of ACE inhibitors?
- dizziness
- headache
- drowsiness
- diarrhea
- low bp
- weakness
- cough
- rash
