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Year 2 Pharmacology > Anxiolytics and Antidepressants > Flashcards

Anxiolytics and Antidepressants Flashcards

1
Q

Antidepressants

A

MAOIs
Tricylic drugs
SSRIs
Lithium

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2
Q

Anxiolytics

A

Sedative-hypnotics
Benzodiazepines
Second generation non-benzodiazepines

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3
Q

Antipsychotics

A

Neuroleptics

Atypical drugs

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4
Q

The classic tricyclic antidepressant drugs inhibit..

A

both serotonin and noradrenaline reuptake into nerve terminals

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5
Q

Examples of Monoamine oxidase inhibitors (MAOIs)

A

Phenetzine - D+Bipolar
Tranylcypromin - severe depression

“cheese effect” Inhibition of cytochrome P450

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6
Q

What do MAOIs do?

A

non-selective blockers of the metabolism of all monaines

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7
Q

Side effects of MAOIs

A

Weight gain
Oedema
Sexual dysfunction
Sedation

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8
Q

Examples of Tacyclic anti-depressants

A

Imipramine - D
Amitripityline - D
Doxepin - Anxiety

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9
Q

What are Tacyclic anti-depressants used for

A

Major depressive episodes
Panic disorders
OCD

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10
Q

Caution and side effects of tacyclic anti-depressants

A

Caution : Pts with MI, coronary instability, avoid CNS depressants

Side effects : weight gain
sexual dysfunction
inhibition of cytochrome p450
sedation
dry mouth 
blurred vision 
constipation
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11
Q

Examples of Selective Serotonin Reuptake Inhibitors (SSRIs)

A

Fluoxetine - D + OCD
Paroxetine - D + Panic
Sertraline - D + Panic
Citalopram - D

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12
Q

Side effects of SSRIs

A

Sexual dysfunction
dependence and withdrawal

Inhibit serotonin uptake
Inhibit reuptake of noradrenaline and serotonin

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13
Q

Other examples of antidepressants

A

Bupropion - D

Venlafazine - D

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14
Q

Example of Sedative Hypnotics (Anxiety)

A

all make you sleep

Thiopental - prep for surgery
Secobarbital
Phenobarbital
Zolpidem

Treatment for insomnia, anxiety, agitation, seizures

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15
Q

Side effect of sedative hypnotics

A

suicidal thoughts

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16
Q

Examples of Benzodiazepines (Anxiety)

‘PAM’

A

Diazepam
Alprazolam
Tenazepam
Lorazepam

17
Q

Side effects for non-benz / benzodiazepines

A 
headache 
dry mouth 
blurred vision
ddizziness
memory loss
hypotension
18
Q

Example of Non-benzodiazepines

19
Q

Two types of drugs to treat psychosis

A

Antipsychotic / neuroleptics

Atypical antipsychotics

20
Q

Examples of Antipsychotic / neuroleptics

A

Chlorpromazine
Fluphenazine
Haloperodol
Loxapine

21
Q

Side effects of Antipsychotic / neuroleptics

A 
Parkinsonism 
Tardive dyskinesia
Hypotension 
Sedation 
Thermoregulation probs
22
Q

Examples of atypical antipsychotics

A

Clozapine
Amisulpride
Rispendone
Olanzepine

23
Q

Side effects of atypical antipsychotics

A 
Photosensitivity 
Headache
Blurred vision
GI probs 
Dizziness
Insomnia

Year 2 Pharmacology (12 decks)

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