Antibiotics

Question 1

Antibiotics interfere with/inhibit

Answer 1

Essential cellular structures and processes

Target bacteria specific structures/processes

Question 2

The cell wall

Answer 2

Is target for many abx
CW is an essential bacteria specific organelle
CW protects bacteria from toxic substances

Question 3

Antibiotics targeting PG biosynthesis are not as effective against

Answer 3

Gram - bacteria

Question 4

Antibiotics that act of PG biosynthesis

Answer 4

Penicillins
Cephalosporins
Carbapenems
(Beta b lactams)

Vancomycin

Kill bacteria by autolysis
Effective against growing and dividing cells

Question 5

Abx that inhibit protein synthesis

Answer 5

Inhibit protein components of 30s subunit:
Tetracycline
Aminoglycosides

Inhibit protein components of 50s subunit
Macrolides
Chloramphenicol

Effective against gram - / +

Question 6

Abx inhibiting DNA biosynthesis

Answer 6

Fluoroquinolone's: 
CiproFLOXACIN
LevoFLOXACIN
NorFLOXACIN
MoxiFLOXACIN

Gram -

Inhibit bacterial enzymes with essential roles in DNA replication

Question 7

Abx inhibiting RNA biosynthesis

Answer 7

Rifampicin

Inhibits bacterial RNA oily erases
Used for TB

Question 8

Biosthynesis of nucleotides requires

Answer 8

Filic acid