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MEDICINAL ORGANIC CHEMISTRY > DRUGS OF CHOICE > Flashcards

DRUGS OF CHOICE Flashcards

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1
Q

ANTIFUNGALS

Cutaneous candidiasis

A

Ciclopirox olamine

Loprox

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2
Q

ANTIFUNGALS

Tinea corporis

A

Ciclopirox olamine

Loprox

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3
Q

ANTIFUNGALS

Tinea cruris

A

Ciclopirox olamine

Loprox

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4
Q

ANTIFUNGALS

Tinea pedis

A

Ciclopirox olamine

Loprox

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5
Q

ANTIFUNGALS

Tinea versicolor

A

Ciclopirox olamine

Loprox

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6
Q

ANTIFUNGALS

Second line agent for onychomycosis (ringworm of the nails)

A

Ciclopirox olamine

Loprox

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7
Q

ANTIFUNGALS

Last option for systemic antifungal therapy due to nephrotoxocity

A

Amphotericin B

Fungizone

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8
Q

ANTIFUNGALS

Cryptococcal Meningitis

A

Fluconazole

Diflucan, Funzela

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9
Q

ANTIFUNGALS

Fungal Meningitis

A

Fluconazole

Diflucan, Funzela

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10
Q

SYNTHETIC ANTIBACTERIALS

Gastroenteritis caused by G. bacilli

A

Ciprofloxacin

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11
Q

SYNTHETIC ANTIBACTERIALS

1st choice for TB prophylaxis

A

Isoniazid

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12
Q

SYNTHETIC ANTIBACTERIALS

2nd choice for TB prophylaxis

A

Rifampicin

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13
Q

SYNTHETIC ANTIBACTERIALS

Short term TB

A

Pyrazinamide

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14
Q

SYNTHETIC ANTIBACTERIALS

Alternative to streptomycin

A

Sterile capreomycin sulfate

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15
Q

ANTI-PROTOZOALS

Amebiasis

A

Metronidazole

Flagyl

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16
Q

ANTI-PROTOZOALS

Giardiasis

A

Metronidazole

Flagyl

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17
Q

ANTI-PROTOZOALS

Trichomoniasis

A

Metronidazole

Flagyl

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18
Q

ANTI-PROTOZOALS

Alternative for Vancomycin in the treatment of pseudomembranous colitis, anti-biotic induced diarrhea, and Clostridium difficile infection

A

Metronidazole

Flagyl

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19
Q

ANTI-PROTOZOALS

Chaga’s disease
(Acute and Chronic)

A

Nifurtimox

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20
Q

ANTI-PROTOZOALS

African Trypanosomiasis
(Later Stages)

A

Melarsoprol

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21
Q

ANTI-PROTOZOALS

Various Leishmaniasis

A

Sodium Stibogluconate

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22
Q

ANTI-PROTOZOALS

African Trypanosomiasis
(Long term prophylaxis)

A

Suramin Sodium

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23
Q

ANTHELMINTHICS

Blood Flukes

A

Praziquantel

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24
Q

ANTHELMINTHICS: NEMATODES

Trichuris

A
  1. Albendazole
  2. Mebendazole

T-AM

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25
Q

ANTHELMINTHICS: NEMATODES

  1. Hookworms
  2. Ascaris lumbricoides (round worm)

Hookworms: Ancylostoma duodenale (old-w) + Necator americanus (new-w)

A
  1. Pyrantel palmoate
  2. Albendazole
  3. Mebendazole

HA-PAM

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26
Q

ANTHELMINTHICS: NEMATODES

Strongyloides

A

Ivermectin

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27
Q

ANTHELMINTHICS: NEMATODES

Enterobius vermivularis

A
  1. Pyrantel palmoate
  2. Mebendazole

E-PM

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28
Q

ANTHELMINTHICS: NEMATODES

Trichinella

A

Mebendazole

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29
Q

ANTHELMINTHICS: NEMATODES

Cutaneous larva migrans

A
  1. Albendazole
  2. Ivermectin

C-AI

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30
Q

ANTHELMINTHICS: NEMATODES

Onchocerca volvulus

A

Ivermectin

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31
Q

ANTHELMINTHICS: TREMATODES

Schistosoma haematobium

A

Praziquantel

32
Q

ANTHELMINTHICS: TREMATODES

Schistosoma mansoni

A

Praziquantel

33
Q

ANTHELMINTHICS: TREMATODES

Schistosoma japonicum

A

Praziquantel

34
Q

ANTHELMINTHICS: TREMATODES

Paragonimus westermani

A

Praziquantel

35
Q

ANTHELMINTHICS: TREMATODES

Fasciola hepatica

A
  1. Bithionol
  2. Triclabendazole
36
Q

ANTHELMINTHICS: TREMATODES

Fasciolopsis buski

A
  1. Praziquantel
  2. Niclosamide
37
Q

ANTHELMINTHICS: CESTODES

Taenia saginata

A
  1. Praziquantel
  2. Niclosamide
38
Q

ANTHELMINTHICS: CESTODES

Taenia solium

A
  1. Praziquantel
  2. Niclosamide
39
Q

ANTHELMINTHICS: CESTODES

Diphylobothrium latum

A
  1. Praziquantel
  2. Niclosamide
40
Q

ANTHELMINTHICS: CESTODES

Hymenolepsis nana

A

Niclosamide

41
Q

ANTHELMINTHICS: CESTODES

Cysticercosis

A

Albendazole

42
Q

ANTHELMINTHICS: CESTODES

Echinococcus granulosus

A

Albendazole

43
Q

DIHYDROFOLATE REDUCTASE INHIBITORS

Complicated and uncomplicated UTI especially caused by entero-bacteria

A

Sulfamethoxazole + Trimethoprim
(Co-trimoxizole)

SMX-TMP

44
Q

SULFONES

Dermatitis Herpetiformis

A

Dapsone, DDS

45
Q

ANTI-MALARIALS: 4-AMINOQUINOLINES

Erythrocytic falciparum malaria except reistsant strains

A

Chloroquine

46
Q

ANTI-MALARIALS: 4-AMINOQUINOLINES

Malarial Suppression

A

Mefloquine

Lariam

47
Q

ANTI-MALARIALS: 8-AMINOQUINOLINES

Acute attack of Plasmodium vivax

A

Primaquine

48
Q

ANTI-MALARIALS: POLYCYCLIC

Leptospira interrogans

A

Doxycycline

49
Q

TETRACYCLINES

Mycoplasma pneumonia

A

Doxycycline

50
Q

TETRACYCLINES

Rickettsial infections

A

Doxycycline

51
Q

TETRACYCLINES

Chlamydia

A

Doxycycline + Azithromycin

52
Q

POLYPEPTIDES

Pseudomembranous colitis

A

Vancomycin

53
Q

UNCLASSIFIED

Typhoid Fever

A

Chloramphenicol

54
Q

ANTIVIRALS

Herpes simplex virus
(HSV)

A

Cytarabine

55
Q

ANTIVIRALS

Herpes simplex virus (HSV) encephalitis

A

Acyclovir

56
Q

ANTIVIRALS

Cytomegalovirus (CMV) retinitis

A

Ganciclovir

57
Q

ANTIVIRALS

Varicella zoster

A

Acyclovir and valacyclovir

58
Q

ANTIVIRALS

Chicken Pox

A

Acyclovir and valacyclovir

59
Q

ANTIVIRALS

CMV retinitis in AIDS patients

A

Cidofovir

60
Q

ANTIVIRALS

2nd line drug for the tx of CMV retinitis in AIDS patients

A

Foscarnet

61
Q

ANTIVIRALS

RSV bronchiolitis

A

Ribavirin

62
Q

ANTIVIRALS

Pneumonia in hospitalized children

A

Ribavirin

63
Q

ANTIVIRALS

Lassa fever

A

Ribavirin

64
Q

ANTINEOPLASTICS

Hodgkin’s disease

A

Mechlorethamine

65
Q

ANTINEOPLASTICS

Chronic lymphocytic leukemia

A

Chlorambucil

66
Q

ANTINEOPLASTICS

Macroglobulinemia

A

Chlorambucil

67
Q

ANTINEOPLASTICS

Metastatic Brain Tumor

A

Lomustine

68
Q

ANTINEOPLASTICS

2nd line agent for Hodgkin’s disease

A

Lomustine

69
Q

ANTINEOPLASTICS

2nd line agent for ovarian cancer

A

Altretamine

70
Q

ANTINEOPLASTICS

Locally advanced or metastatic adenocarcinoma of the pancreas

A

Gemcitabine + Cisplatin

71
Q

ANTINEOPLASTICS

Inoperable locally advanced or metastatic NSCLC

A

Gemcitabine

72
Q

ANTINEOPLASTICS

Paget’s Disease

A

Plicamycin

73
Q

ANTINEOPLASTICS

Metastatic Colon Cancer

A

5-FU + Leucovorin + Irinotecan

74
Q

ANTINEOPLASTICS

2nd line single agent in colorectal cancer

A

Irinotecan

75
Q

ANTIVIRALS

Hepatitis B

A

Adefovir

MEDICINAL ORGANIC CHEMISTRY (17 decks)

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