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MEDICINAL ORGANIC CHEMISTRY > DRUGS OF CHOICE > Flashcards

DRUGS OF CHOICE Flashcards

1
Q

ANTIFUNGALS

Cutaneous candidiasis

A

Ciclopirox olamine

Loprox

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2
Q

ANTIFUNGALS

Tinea corporis

A

Ciclopirox olamine

Loprox

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3
Q

ANTIFUNGALS

Tinea cruris

A

Ciclopirox olamine

Loprox

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4
Q

ANTIFUNGALS

Tinea pedis

A

Ciclopirox olamine

Loprox

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5
Q

ANTIFUNGALS

Tinea versicolor

A

Ciclopirox olamine

Loprox

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6
Q

ANTIFUNGALS

Second line agent for onychomycosis (ringworm of the nails)

A

Ciclopirox olamine

Loprox

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7
Q

ANTIFUNGALS

Last option for systemic antifungal therapy due to nephrotoxocity

A

Amphotericin B

Fungizone

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8
Q

ANTIFUNGALS

Cryptococcal Meningitis

A

Fluconazole

Diflucan, Funzela

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9
Q

ANTIFUNGALS

Fungal Meningitis

A

Fluconazole

Diflucan, Funzela

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10
Q

SYNTHETIC ANTIBACTERIALS

Gastroenteritis caused by G. bacilli

A

Ciprofloxacin

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11
Q

SYNTHETIC ANTIBACTERIALS

1st choice for TB prophylaxis

A

Isoniazid

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12
Q

SYNTHETIC ANTIBACTERIALS

2nd choice for TB prophylaxis

A

Rifampicin

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13
Q

SYNTHETIC ANTIBACTERIALS

Short term TB

A

Pyrazinamide

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14
Q

SYNTHETIC ANTIBACTERIALS

Alternative to streptomycin

A

Sterile capreomycin sulfate

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15
Q

ANTI-PROTOZOALS

Amebiasis

A

Metronidazole

Flagyl

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16
Q

ANTI-PROTOZOALS

Giardiasis

A

Metronidazole

Flagyl

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17
Q

ANTI-PROTOZOALS

Trichomoniasis

A

Metronidazole

Flagyl

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18
Q

ANTI-PROTOZOALS

Alternative for Vancomycin in the treatment of pseudomembranous colitis, anti-biotic induced diarrhea, and Clostridium difficile infection

A

Metronidazole

Flagyl

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19
Q

ANTI-PROTOZOALS

Chaga’s disease
(Acute and Chronic)

A

Nifurtimox

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20
Q

ANTI-PROTOZOALS

African Trypanosomiasis
(Later Stages)

A

Melarsoprol

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21
Q

ANTI-PROTOZOALS

Various Leishmaniasis

A

Sodium Stibogluconate

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22
Q

ANTI-PROTOZOALS

African Trypanosomiasis
(Long term prophylaxis)

A

Suramin Sodium

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23
Q

ANTHELMINTHICS

Blood Flukes

A

Praziquantel

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24
Q

ANTHELMINTHICS: NEMATODES

Trichuris

A
  1. Albendazole
  2. Mebendazole

T-AM

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25
# ANTHELMINTHICS: NEMATODES 1. Hookworms 2. Ascaris lumbricoides (round worm) | Hookworms: Ancylostoma duodenale (old-w) + Necator americanus (new-w)
1. Pyrantel palmoate 2. Albendazole 3. Mebendazole | HA-PAM
26
# ANTHELMINTHICS: NEMATODES Strongyloides
Ivermectin
27
# ANTHELMINTHICS: NEMATODES Enterobius vermivularis
1. Pyrantel palmoate 2. Mebendazole | E-PM
28
# ANTHELMINTHICS: NEMATODES Trichinella
Mebendazole
29
# ANTHELMINTHICS: NEMATODES Cutaneous larva migrans
1. Albendazole 2. Ivermectin | C-AI
30
# ANTHELMINTHICS: NEMATODES Onchocerca volvulus
Ivermectin
31
# ANTHELMINTHICS: TREMATODES Schistosoma haematobium
Praziquantel
32
# ANTHELMINTHICS: TREMATODES Schistosoma mansoni
Praziquantel
33
# ANTHELMINTHICS: TREMATODES Schistosoma japonicum
Praziquantel
34
# ANTHELMINTHICS: TREMATODES Paragonimus westermani
Praziquantel
35
# ANTHELMINTHICS: TREMATODES Fasciola hepatica
1. Bithionol 2. Triclabendazole
36
# ANTHELMINTHICS: TREMATODES Fasciolopsis buski
1. Praziquantel 2. Niclosamide
37
# ANTHELMINTHICS: CESTODES Taenia saginata
1. Praziquantel 2. Niclosamide
38
# ANTHELMINTHICS: CESTODES Taenia solium
1. Praziquantel 2. Niclosamide
39
# ANTHELMINTHICS: CESTODES Diphylobothrium latum
1. Praziquantel 2. Niclosamide
40
# ANTHELMINTHICS: CESTODES Hymenolepsis nana
Niclosamide
41
# ANTHELMINTHICS: CESTODES Cysticercosis
Albendazole
42
# ANTHELMINTHICS: CESTODES Echinococcus granulosus
Albendazole
43
# DIHYDROFOLATE REDUCTASE INHIBITORS Complicated and uncomplicated UTI especially caused by entero-bacteria
Sulfamethoxazole + Trimethoprim (Co-trimoxizole) | SMX-TMP
44
# SULFONES Dermatitis Herpetiformis
Dapsone, DDS
45
# ANTI-MALARIALS: 4-AMINOQUINOLINES Erythrocytic falciparum malaria except reistsant strains
Chloroquine
46
# ANTI-MALARIALS: 4-AMINOQUINOLINES Malarial Suppression
Mefloquine | Lariam
47
# ANTI-MALARIALS: 8-AMINOQUINOLINES Acute attack of Plasmodium vivax
Primaquine
48
# ANTI-MALARIALS: POLYCYCLIC Leptospira interrogans
Doxycycline
49
# TETRACYCLINES Mycoplasma pneumonia
Doxycycline
50
# TETRACYCLINES Rickettsial infections
Doxycycline
51
# TETRACYCLINES Chlamydia
Doxycycline + Azithromycin
52
# POLYPEPTIDES Pseudomembranous colitis
Vancomycin
53
# UNCLASSIFIED Typhoid Fever
Chloramphenicol
54
# ANTIVIRALS Herpes simplex virus (HSV)
Cytarabine
55
# ANTIVIRALS Herpes simplex virus (HSV) encephalitis
Acyclovir
56
# ANTIVIRALS Cytomegalovirus (CMV) retinitis
Ganciclovir
57
# ANTIVIRALS Varicella zoster
Acyclovir and valacyclovir
58
# ANTIVIRALS Chicken Pox
Acyclovir and valacyclovir
59
# ANTIVIRALS CMV retinitis in AIDS patients
Cidofovir
60
# ANTIVIRALS 2nd line drug for the tx of CMV retinitis in AIDS patients
Foscarnet
61
# ANTIVIRALS RSV bronchiolitis
Ribavirin
62
# ANTIVIRALS Pneumonia in hospitalized children
Ribavirin
63
# ANTIVIRALS Lassa fever
Ribavirin
64
# ANTINEOPLASTICS Hodgkin's disease
Mechlorethamine
65
# ANTINEOPLASTICS Chronic lymphocytic leukemia
Chlorambucil
66
# ANTINEOPLASTICS Macroglobulinemia
Chlorambucil
67
# ANTINEOPLASTICS Metastatic Brain Tumor
Lomustine
68
# ANTINEOPLASTICS 2nd line agent for Hodgkin's disease
Lomustine
69
# ANTINEOPLASTICS 2nd line agent for ovarian cancer
Altretamine
70
# ANTINEOPLASTICS Locally advanced or metastatic adenocarcinoma of the pancreas
Gemcitabine + Cisplatin
71
# ANTINEOPLASTICS Inoperable locally advanced or metastatic NSCLC
Gemcitabine
72
# ANTINEOPLASTICS Paget's Disease
Plicamycin
73
# ANTINEOPLASTICS Metastatic Colon Cancer
5-FU + Leucovorin + Irinotecan
74
# ANTINEOPLASTICS 2nd line single agent in colorectal cancer
Irinotecan
75
# ANTIVIRALS Hepatitis B
Adefovir

MEDICINAL ORGANIC CHEMISTRY (17 decks)

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