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MEDICINAL ORGANIC CHEMISTRY > ANTI-INFECTIVES: PHENOLS + OXIDIZING AGENTS > Flashcards

ANTI-INFECTIVES: PHENOLS + OXIDIZING AGENTS Flashcards

1
Q

Substitution with alkyl, aryl, and halogen, especially in the ____ position, increases bactericidal activity of phenols

A

Para

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2
Q

Alkylated phenols and resorcinols are less toxic than the parent compounds while retaining bactericidal properties.

True or False

A

True

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3
Q

SYNONYMS

Methyl phenol

A

Cresol

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4
Q

The standard to which most germicides are compared

A

Phenol, USP

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5
Q

Phenol is a colorless to ____ crystalline (solid) material with characteristic “____ odor.”

A

Pale pink, medicinal

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6
Q

____ is added to make phenol milder.

Phenol is a protoplasmic poison.

A

Glycerol

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7
Q

This is used to cauterize small wounds.

A

Phenol-glycerin

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8
Q

Phenolated Calamine Lotion is used as ____.

A

Anti-pruritic

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9
Q

Phenol with 10% water that is used as pharmaceutical aid

A

Liquefied Phenol

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10
Q

Phenol coefficient of p-chlorophenol

A

4

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11
Q

This is used in combination with camphor in liquid petrolatum.

A

p-chlorophenol

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12
Q

Used externally as antiseptic and anti-irritant

A

p-chlorophenol

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13
Q

Available as shampoo which is used for the treatment of fungal infection

A

p-chloro-m-xylenol

PC-MX, Metasep

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14
Q

A bisphenolic, more potent than monophenolic, easily absorbed onto skin and even sebaceous glands

A

Hexachlorophene

Gamophen

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15
Q

Phenol coefficient of cresol

A

2.5

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16
Q

Yellow to brownish-yellow liquid that has a characteristic creosote odor

17
Q

Cresol is used as an ____ and ____.

A

Antiseptic, Disinfectant

18
Q

Cresol is obtained from ____.

A

Coal Tar or Petroleum

19
Q

A colorless crystal and used as preservative

A

Chlorocresol
(4-chloro-3-methyl-phenol)

20
Q

Antifungal for the treatment of Tinea capitis, Tinea corpus

A

Thymol
(isopropyl m-cresol)

21
Q

SYNONYMS

Chlorocresol

A

4-chloro-3-methyl-phenol

22
Q

SYNONYMS

Thymol

A

isopropyl m-cresol

23
Q

SYNONYMS

Eugenol

A

4-allyl-2-methylphenol

24
Q

SYNONYMS

Resorcinol

A

m-dihydroxybenzene, resorcin

25
Q

Phenol derivative that is capable of eutexia.

26
Q

Resorcinol is usually combined with ____ to be used as a keratolytic/antifungal.

A

Salicylic Acid

27
Q

OXIDIZING AGENTS: SYNONYMS

Gly-Oxide

A

Carbamideperoxide Topical Solution

28
Q

OXIDIZING AGENTS: SYNONYMS

Oxy-5 and 10, Vamoxide, Panoxyl

A

Hydrous Benzoyl Peroxide

29
Q

OXIDIZING AGENTS:

A white granular powder, explosive (pure) addition of 30% water to make it safer

A

Hydrous Benzoyl Peroxide

30
Q

OXIDIZING AGENTS:

Propionic bacterium acnes are treated by ____.

A

Hydrous Benzoyl Peroxide

31
Q

OXIDIZING AGENTS:

Mechanism of action of Hydrous Benzoyl Peroxide

A

Proliferation of epithelial cells

MEDICINAL ORGANIC CHEMISTRY (17 decks)

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