Drugs of abuse - PCP, GHB, cannabis, heroin

Question 1

what is PCP

Answer 1

dissociative anasthetic with hallucinogenic properties

Question 2

what was pcp used for

Answer 2

iv anaesthetic for humans stopped due to side effects

then a vet anasthetic

Question 3

sources of PCP

Answer 3

illicit only

easy to manufacture

Question 4

methods of pcp ingestion

Answer 4

smoked most common
applied in powder or liquid form to leafy substances such as mint which can then be smoked
oral ingestion
injection
eye dropper
snorting
inhalation
skin

Question 5

desired effects of pcp

Answer 5

intense euphoria
hallucination
relaxation
dissociation from the environment

Question 6

onset of pcp

Answer 6

1-5min smoked

Question 7

duration of pcp

Answer 7

4-6hr

Question 8

other effects of pcp

Answer 8

agitation, confusion
increased pain threshold
moon walking
cyclic: agitated then calm

Question 9

toxicity pcp symptoms

Answer 9

delirium
hallucination
convulsion
violent reactions
long term use = psychosis

Question 10

overdose of pcp

Answer 10

coma
seizure
death due to respiratory arrest

Question 11

dependencies of pcp

Answer 11

tolerance
psychological dependence
no physiological

Question 12

another dissociative anaesthetic like pcp

Answer 12

dextromethorphan in high doses

Question 13

what is GHB

Answer 13

gabba hydroxybutyrate

cns depressant

Question 14

use of GHB

Answer 14

recreational
date rape drug
experimental drug for treatment of nacrolepsy

Question 15

sources of GHB

Answer 15

illigal to manufacture or sell in canada
recipes on internet easy to make only have 2 ingredients in paint thinner
liquid or powder

Question 16

how to make GHB

Answer 16

strong base and solvent used in paint thinner

unneutalized base can burn the throat

Question 17

methods of GHB ingestion

Answer 17

oral - capful of liquid, powder mixed with liquid

Question 18

why is GHB mixed in tasty drinks

Answer 18

salty taste

Question 19

desired effects of GHB

Answer 19

relaxation
sense of well being
loss of social inhibitions

Question 20

GHB onset and duration

Answer 20

5-20min

2-3hr

Question 21

problems with GHB detection for police

Answer 21

only detectable in blood for 6hr and urine for 12hr
short window of time for testing assault
cant test drinks for it

Question 22

other effects of GHB

Answer 22

amnesia
drowsy
slurred speech
loss of balance
like alcohol kinda

Question 23

high doses of GHB cause

Answer 23

loss of consciousness
slowed heart rate
seizure
coma
death

Question 24

problems with interpretation of GHB

Answer 24

endogenous metabolite produced by body so have to determine concentration
may be a product of postmortem decomposition
special tests requires for screening - not done routinely
severl analogs of GHB are abused

Question 25

properties of cannabis

Answer 25

cns depression stimulant hallucinogenic

Question 26

cannabis uses

Answer 26

fiber to make clothing hemp seeds for food and oil variaety of conditions mainly recreational

Question 27

medical marihuana used for

Answer 27

antiemetic - NV in cancer glaucoma antispasmodic appetite enhancer - AIDS

Question 28

what is dronabinol

Answer 28

synthetic trans isomer of THC

Question 29

what is nabilone

Answer 29

synthetic chromenine derivative of THC

Question 30

what is sativex

Answer 30

natural THC and cannabidiol | used for neuropathic pain and spasticity in MS

Question 31

sources of cannabis

Answer 31

cannabis sativa plant sinsemilla - female plant highest THC hash and hash oil

Question 32

method of cannabis ingestion

Answer 32

smoking - joint, bong, blunt | oral ingestion

Question 33

desired cannabis effects

Answer 33

euphoria relaxation loss of inhibitions sense of wellbeing

Question 34

onset of cannabis smoking

Answer 34

8-9 sec

Question 35

duration of cannabis

Answer 35

2-3hr

Question 36

other effects of cannabis

Answer 36

``` distort time impairmemory and concentration confusion reduced ability to process info balance difficulty spontaneous laughter munchies dry mouth ```

Question 37

toxicity of canabis

Answer 37

``` fearfulness anxiety paranoria more common when ingested orally, first time, or chronic high doses no known deaths ```

Question 38

can passive inhalation get you high

Answer 38

would require very extreme conditions with so much weed in the air

Question 39

why does thc stay in blood and urine for a long time

Answer 39

fat soluble | used every day for a year would stay positive for 8weeks

Question 40

problems with cannabis interpretation

Answer 40

degrades with freeze thaw cycle | have to do oral test and standard sobriety then take to hospital for a blood test

Question 41

what is heroin

Answer 41

narcotic analgesic that is 2-3x more potent then morphine | diacetylmorphine

Question 42

sources of heroin

Answer 42

produced by treating morphine wiht acetic anhydride | powder or tar

Question 43

methods of heroin ingestion

Answer 43

injection smoking snorting

Question 44

desired effects of heroin

Answer 44

euphoria sense of well being relief of pain

Question 45

onset of heroin

Answer 45

immediiate euphoria | 25 min for physical effects

Question 46

duration of heroin

Answer 46

3-6hr physical effects

Question 47

other heroin effects

Answer 47

``` on the nod semiconscious droopy eyelid head slumped on chest easily awakened alert to questions pinpoint pupils facial itching nausea slow deliberate movements ```

Question 48

pupils in abused drugs

Answer 48

constricted for opioids, heroin (except demerol) | dilated for cocaine and stimulants

Question 49

toxicity of heroin

Answer 49

resp depression | coma death

Question 50

treatment of heroin od

Answer 50

naloxone

Question 51

dependence associated with heroin

Answer 51

tolerance psychological dependence physiological dependence

Question 52

describe heroin physiological dependence

Answer 52

``` withdrawl in 4-6h peak in 24-36 insomnia, vomiting, diarhea, hot and cold, weakness, cold like rebound pupil dilation treat with methadone ```

Question 53

interpretation challanges of heroin

Answer 53

not detected in body fluids requires a special extraction procedures wide range of concentrations are seen in deaths amphoteric: base and acid, requires extraction at ph =8