Drugs of abuse Flashcards
sources of cocaine
mostly as HCl salt
crack - free base form not water soluble
methods of cocaine ingestion
IV smoking - crack snorting oral rare due to first pass effect topically free basing - make HCl into crack
desired cocaine effects
intense euphoria
decreased anxiety and social inhibtions
increased alertness, mental clarity, performance in simple tasks, self confidence
onset of cocaine effect
7sec smoking
10min oral
duration of cocaine effects
20min smoking
60min oral
90min snorting
high dose chronic cocaine use effects
dysphoria fatigue confusion hallucinations fear and paranoria aggressiveness itching of skin psychosis
what is formucation
sensaton of bugs under skin
3 phases of cocaine withdrawal
crash phase: agitation, depression, intense cravings, fatigue lasts 4 days
withdrawal phase: increased anxiety, lack of energy, variable cravings lasts up to 10weeks
extinction phase: episodic cravings for the drug
symptoms of cocaine induced excited delirium
dissociative state violence exaggerated strength increased BP cardiorespiratory arrest rhabdomyolysis sudden death
type of dependences developed from cocaine use
tolerance
psychological
physiological
challenges interpretating cocaine use
enzymes in the blood cause a loss of cociaine
alcohol + cocaine makes cocaethylene metabolite
sources of meth
super labs that use bulk quantities of the required substances
small clandestine labs in NA
meth is made from
pseudoephedrine or ephedrine
paint thinner
drain cleaner
starter fluid etc
how did mb pharmacists try control meth production
max pseudoephedrine sold at one time 3600mg
3 methods of meth production
P2P
ephedrine or pseudoephedrine reduction
nazi methods
