Drugs for Urinary Tract Disorders Flashcards

1
Q

pyelonephritis is

A

an upper UTI

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2
Q

cystitis is

A

a lower UTI

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3
Q

Acute cystitis can be caused by

A

E. coli
Staph
Klebsiella
Pseudomonas

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4
Q

Symptoms of acute cystitis and prostatitis are

A

pain and burning on urination, frequency, urgency

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5
Q

The majority of urinary tract disorders are caused by

A

UTIs

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6
Q

pyelonephritis is most commonly caused by

A

E. coli

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7
Q

symptoms of pyelonephritis are

A
chills 
fever
flank pain
pyuria
painful urination
frequency
urgency
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8
Q

Urinary antiseptics/antiinfectives include

A

nitrofurantoin, methenamine, trimethoprim, and the fluoroquinolones

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9
Q

The action of nitrofurantoin is

A

it is a bacteriostatic or bactericidal antibiotic that inhibits bacterial enzymes and metabolism.

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10
Q

Nitrofurantoin is effective against

A

gram+ and gram-

E. coli

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11
Q

Nitrofurantoin can be used in low doses to

A

prevent bacterial growth in the bladder and kidneys

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12
Q

Side effects for nitrofurantoin include

A
rash, pruritus
dizziness, HA, drowsiness
GI distress
pulmonary reactions (dyspnea, chest pain, fever, cough)
Rust-colored or brown urine
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13
Q

Adverse reactions for nitrofurantoin include

A
Stevens-Johnson syndrome
superinfection
hepatotoxicity
blood dyscrasias
peripheral neuropathy
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14
Q

Interventions for nitrofurantoin include

A
Take with food
Shake suspension well
Rinse mouth after taking
avoid antacids
Do not crush or open caps
Do not drive 
increase fluid intake
consume cranberry juice, plums, proteins and vitamin c
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15
Q

The action of methenamine hippurate (Hiprex) is

A

Bactericidal when urine is acidic

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16
Q

Methenamine hippurate is effective against

A

gram+ and gram-
E. coli
P. aeruginosa
pseudomonas

17
Q

Methenamine hippurate is used for ______ UTIs

18
Q

To decrease the pH of urine a patient can ingest

A

cranberry juice (several glasses/d)
ascorbic acid
ammonium chloride

19
Q

Methenamine should not be taken with

A

sulfonamides

this would cause crystalluria

20
Q

The action of phenazopyridine (Pyridium) is

A

to relieve pain, burning sensation, frequency and urgency

21
Q

The side effects/ adverse reactions of phenazopyridine (Pyridium) is

A
GI upset (NVD)
nephrotoxicity
hepatotoxicity
Blood dyscrasia
Red-orange urine
glucose test alterations (monitor)
22
Q

The action of bethanechol is

A

to increase bladder tone of the detrusor muscle (stimulant)

23
Q

Bethanechol is used to treat

A

hypotonic bladder

24
Q

Bethanechol is contraindicated with

A

peptic ulcer, COPD

25
Side effects and adverse reactions of bethanechol are
dizziness, fainting, and GI distress,
26
The action of oxybutynin is
direct action on smooth muscle to relieve spasms
27
The side effects of oxybutynin are
drowsiness, dizziness, fatigue blurred vision, dry mouth tachycardia constipation
28
oxybutynin is contraindicated with
glaucoma Urinary and GI obstructions cardiac, renal, hepatic, and prostate problems as they have the same effects as anticholinergics
29
The action of tolterodine tartrate anticholinergic is
to control overactive bladder
30
The side effects of tolterodine tartrate are
``` drowsiness dizziness fainting blurred vision dry mouth tachycardia constipation ```
31
Contraindications for tolterodine tartrate are
glaucoma cardiac, renal, hepatic, and prostate problems Client should report urinary retention
32
Nitrofurantoin is used to treat
acute or chronic UTIs