Drugs for Urinary Tract Disorders Flashcards
pyelonephritis is
an upper UTI
cystitis is
a lower UTI
Acute cystitis can be caused by
E. coli
Staph
Klebsiella
Pseudomonas
Symptoms of acute cystitis and prostatitis are
pain and burning on urination, frequency, urgency
The majority of urinary tract disorders are caused by
UTIs
pyelonephritis is most commonly caused by
E. coli
symptoms of pyelonephritis are
chills fever flank pain pyuria painful urination frequency urgency
Urinary antiseptics/antiinfectives include
nitrofurantoin, methenamine, trimethoprim, and the fluoroquinolones
The action of nitrofurantoin is
it is a bacteriostatic or bactericidal antibiotic that inhibits bacterial enzymes and metabolism.
Nitrofurantoin is effective against
gram+ and gram-
E. coli
Nitrofurantoin can be used in low doses to
prevent bacterial growth in the bladder and kidneys
Side effects for nitrofurantoin include
rash, pruritus dizziness, HA, drowsiness GI distress pulmonary reactions (dyspnea, chest pain, fever, cough) Rust-colored or brown urine
Adverse reactions for nitrofurantoin include
Stevens-Johnson syndrome superinfection hepatotoxicity blood dyscrasias peripheral neuropathy
Interventions for nitrofurantoin include
Take with food Shake suspension well Rinse mouth after taking avoid antacids Do not crush or open caps Do not drive increase fluid intake consume cranberry juice, plums, proteins and vitamin c
The action of methenamine hippurate (Hiprex) is
Bactericidal when urine is acidic