drugs for Neurodegenerative disorders Flashcards

1
Q

Parkinsons drugs

A

Pramipexole
Ropinirole
Bromocriptine

Levodopa

Carbidopa

Entacapone and Tolcapone

Amantidine

Benztropinbe and Trihexyphenidyl

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2
Q

Alzheimer’s drugs

A

Galantamine, Rivastigmine, Donepezil, and Tacrine

Memantine

Nootropics

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3
Q

Nootropic drugs

A
  1. Piracetam
    - Unclear mechanism, may increase AMPA signaling,
    ADh signaling
    - Decreases platelet aggregation
    - Stimulates cerebral vasodilation
  2. Nicergoline
    Ergot derivative alpha inhibitor, increased blood flow

3.Ginkgo biloba and other antioxidants: Vitamin C, E

  1. Nimodipine
    CCB, increased cerebral blood flow
  2. Trophic factors: NGH
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4
Q

Drug for AML

A

• Riluzole – Na channel blocker, increases survival 2 months

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5
Q

Drugs for Wilson’s disease

A

Excessive copper accumulation

• Rx: D-Penicillamine, Trientien –Copper chelators,

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