drugs for Neurodegenerative disorders Flashcards
1
Q
Parkinsons drugs
A
Pramipexole
Ropinirole
Bromocriptine
Levodopa
Carbidopa
Entacapone and Tolcapone
Amantidine
Benztropinbe and Trihexyphenidyl
2
Q
Alzheimer’s drugs
A
Galantamine, Rivastigmine, Donepezil, and Tacrine
Memantine
Nootropics
3
Q
Nootropic drugs
A
- Piracetam
- Unclear mechanism, may increase AMPA signaling,
ADh signaling
- Decreases platelet aggregation
- Stimulates cerebral vasodilation - Nicergoline
Ergot derivative alpha inhibitor, increased blood flow
3.Ginkgo biloba and other antioxidants: Vitamin C, E
- Nimodipine
CCB, increased cerebral blood flow - Trophic factors: NGH
4
Q
Drug for AML
A
• Riluzole – Na channel blocker, increases survival 2 months
5
Q
Drugs for Wilson’s disease
A
Excessive copper accumulation
• Rx: D-Penicillamine, Trientien –Copper chelators,