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NUR 203 Pharm II > Drugs for Coagulation Disorders > Flashcards

Drugs for Coagulation Disorders Flashcards

1
Q

Where are blood cells made?

A

Bone marrow

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2
Q

What are RBCs for?

A

O2 and CO2 transport

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3
Q

What are WBCs for?

A

Immunity & inflammation

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4
Q

What are platelets?

A

Clotting factors

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5
Q

What blood cell establishes homeostasis in blood flow?

A

platelets

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6
Q

What causes thrombosis?

A

Too much coagulation or platelets
Impaired fibrinolysis

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7
Q

What causes hemorrhage?

A

Not enough coagulation or platelets
Too much fibrinolysis

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8
Q

What factors are needed for platelet aggregation?

A

GP2, B2, B3

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9
Q

What are the types of hemostasis?

A

primary and secondary

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10
Q

What is the final product of primary hemostasis?

A

Platelet activation & aggregation

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11
Q

What are the pathways of secondary hemostasis?

A

Intrinsic and extrinsic pathway

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12
Q

Where do the pathways of secondary hemostasis meet?

A

Formation of factor Xa

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13
Q

What is the final product of secondary hemostasis?

A

Fibrin –> clot formed

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14
Q

What vitamin is needed for most clotting factor formation?

A

Vitamin K

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15
Q

What condition is at risk for throwing a clot after cardioversion?

A

A fib

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16
Q

What is a pt with A fib after cardioverting with electricity or antidysrhythmic medications?

A

throwing a clot

17
Q

Why are pts with A fib often on an anticoagulant?

A

prevent throwing a clot

18
Q

Why is aspirin NOT used to prevent DVT?

A

It is an antiplatelet that prevents arterial thrombi

19
Q

How long do platelets live?

A

7-10 days

20
Q

How long does aspirin TE last after d/c?

A

7-10 days because it permanently inhibits platelets from aggregating, so only when the old platelets effected by aspirin die the TE goes away

21
Q

What bones does hematopoiesis take place in adults?

A

Pelvis
Sternum
Ribs
Vertebra

NUR 203 Pharm II (12 decks)

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