Drugs for Anemia and Coagulation Disorders Flashcards
Oral Drugs used in iron deficiency anemia
Ferrous sulfate (65 mg) Ferrous gluconate (36 mg) Ferrous fumarate (106 mg)
Parenteral drugs used in iron deficiency anemia
Iron Dextran
Sodium Ferric gluconate complex
Iron sucrose
In patients treated for anemia, necrotizing gastroenteritis, abdominal pain, bloody diarrhea, shock, lethargy and dyspnea are symptoms of what?
Acute overdose
What is the result of chronic iron overload?
Hematochromatosis
what is the treatment for acute iron poisoning?
Deferoxamine, Deferasirox
What is used in the treatment for anemia associated with chronic renal disease which is also used as performing enhancing drug in athletes
Epoetin alfa
What is the treatment in neutropenia associated with chemotherapy, myelodysplasia, and aplastic anemia
G-CSF
Sargramostim, Pegfilgrastim
What is one of the side effects of giving epoetin alfa?
Pure red cell aplasia
What is a megakarocyte growth factor used in the secondary prevention of thrombocytopenia in patients undergoing cytotoxic chemotherapy and acts by activating IL-11 receptors?
Oprelvekin (IL-11)
What is the toxic dose of aspirin? Lethal Dose?
Toxic dose: 150 mg/kg
Lethal dose: 500 mg/kg
what is the triad of aspirin hypersensitivity?
SAMTER’s triad: Asthma, Aspirin Sensitivity, Nasal polyps
What is an antiplatelet drug that acts by inhibiting GPIIB/IIIa binding to fibrinogen and other ligands
Abciximab, Eptifibatide, tirofiban